Short Report: Identification of Virulence-Associated Plasmids in Rhodococcus equi in Humans with and without Acquired Immunodeficiency Syndrome in Brazil

Autor(es)

Ribeiro, Marcio Garcia ^[1] ; Takai, Shinji ^[2] ; de Vargas, Agueda Castagna ^[3] ; Mattos-Guaraldi, Ana Luiza ^[4] ; Ferreira Camello, Thereza Cristina ^[4] ; Ohno, Ryoko ^[2] ; Okano, Hajime ^[2] ; da Silva, Aristeu Vieira ^[5]

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista, Fac Med Vet & Zootecnia, Dept Higiene Vet & Saude Publ, BR-18618970 Sao Paulo - Brazil

^[2] Kitasato Univ, Sch Vet Med & Anim Sci, Dept Anim Hyg, Towada, Aomori 0348628 - Japan

^[3] Univ Fed Santa Maria, Dept Med Vet Prevent, Ctr Ciencias Rurais, BR-97105900 Santa Maria, RS - Brazil

^[4] Univ Estado Rio de Janeiro, Fac Ciencias Med, BR-20551030 Rio De Janeiro - Brazil

^[5] Univ Feira de Santana, Dept Biol Sci, BR-44036900 Feira De Santana, BA - Brazil

• Tipo de documento: Artigo Científico
• Fonte: American Journal of Tropical Medicine and Hygiene; v. 85, n. 3, p. 510-513, SEP 2011.
• Citações Web of Science: 10

Resumo

Virulence of Rhodococcus equi strains from 20 humans in Brazil was investigated by using a polymerase chain reaction to characterize isolates as virulent (VapA), intermediately virulent (VapB), and avirulent. Nine isolates were obtained from human immunodeficiency virus (HIV)-positive patients, six from HIV-negative patients, and five from patients of unknown status. Five isolates were VapB positive, four were VapA positive, and eleven were avirulent. Among the nine isolates from HIV-positive patients, five contained VapB plasmids and two contained VapA plasmids. Five VapB-positive isolates had the type 8 virulence plasmid. Eleven of the patients had a history of contact with livestock and/or a farm environment, and none had contact with pigs. (AU)

• Processo FAPESP: 06/50406-0 - Fatores de virulência, epidemiologia molecular e reflexos em saúde pública de linhagens de Rhodococcus equi isoladas de animais, do homem e do ambiente
• Beneficiário: Marcio Garcia Ribeiro
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores