Cesarean delivery is associated with an increased risk of obesity in adulthood in a Brazilian birth cohort study

Autor(es)

Goldani, Helena A. S. ^[1] ; Bettiol, Heloisa ^[2] ; Barbieri, Marco A. ^[2] ; Silva, Antonio A. M. ^[3] ; Agranonik, Marilyn ^[1] ; Morais, Mauro B. ^[4] ; Goldani, Marcelo Z. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Dept Pediat, Fac Med, BR-90013590 Porto Alegre, RS - Brazil

^[2] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Pediat, Ribeirao Preto - Brazil

^[3] Univ Fed Maranhao, Fac Med, Dept Publ Hlth, Sao Luis, Maranhao - Brazil

^[4] Univ Fed Sao Paulo, Dept Pediat, Fac Med, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: AMERICAN JOURNAL OF CLINICAL NUTRITION; v. 93, n. 6, p. 1344-1347, JUN 2011.
• Citações Web of Science: 57

Resumo

Background: Obesity is epidemic worldwide, and increases in cesarean delivery rates have occurred in parallel. Objective: This study aimed to determine whether cesarean delivery is a risk factor for obesity in adulthood in a birth cohort of Brazilian subjects. Design: We initiated a birth cohort study in Ribeirao Preto, southeastern Brazil, in 1978. A randomly selected sample of 2057 subjects from the original cohort was reassessed in 2002-2004. Type of delivery, birth weight, maternal smoking, and schooling were obtained after birth. The following data from subjects were collected at 23-25 y of age: body mass index (BMI; in kg/m(2)), physical activity, smoking, and income. Obesity was defined as a BMI >= 30. A Poisson multivariable model was performed to determine the association between cesarean delivery and BMI. Results: The obesity rate in adults born by cesarean delivery was 15.2% and in those born by vaginal delivery was 10.4% (P = 0.002). Adults born by cesarean delivery had an increased risk (prevalence ratio: 1.58; 95% CI: 1.23, 2.02) of obesity at adulthood after adjustments. Conclusion: We hypothesize that increasing rates of cesarean delivery may play a role in the obesity epidemic worldwide. Am J Clin Nutr 2011;93:1344-7. (AU)

• Processo FAPESP: 00/09508-7 - Da saúde perinatal à saúde do adulto jovem: estudo da coorte nascida em 1978/79 nos hospitais de Ribeirão Preto, SP
• Beneficiário: Marco Antonio Barbieri
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 97/09517-1 - Estudo epidemiológico-social longitudinal da saúde da criança de uma coorte em 3 momentos: ao nascer, na idade escolar e aos 18 anos
• Beneficiário: Marco Antonio Barbieri
• Modalidade de apoio: Auxílio à Pesquisa - Regular