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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cesarean delivery is associated with an increased risk of obesity in adulthood in a Brazilian birth cohort study

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Author(s):
Goldani, Helena A. S. [1] ; Bettiol, Heloisa [2] ; Barbieri, Marco A. [2] ; Silva, Antonio A. M. [3] ; Agranonik, Marilyn [1] ; Morais, Mauro B. [4] ; Goldani, Marcelo Z. [1]
Total Authors: 7
Affiliation:
[1] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Dept Pediat, Fac Med, BR-90013590 Porto Alegre, RS - Brazil
[2] Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Pediat, Ribeirao Preto - Brazil
[3] Univ Fed Maranhao, Fac Med, Dept Publ Hlth, Sao Luis, Maranhao - Brazil
[4] Univ Fed Sao Paulo, Dept Pediat, Fac Med, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: AMERICAN JOURNAL OF CLINICAL NUTRITION; v. 93, n. 6, p. 1344-1347, JUN 2011.
Web of Science Citations: 57
Abstract

Background: Obesity is epidemic worldwide, and increases in cesarean delivery rates have occurred in parallel. Objective: This study aimed to determine whether cesarean delivery is a risk factor for obesity in adulthood in a birth cohort of Brazilian subjects. Design: We initiated a birth cohort study in Ribeirao Preto, southeastern Brazil, in 1978. A randomly selected sample of 2057 subjects from the original cohort was reassessed in 2002-2004. Type of delivery, birth weight, maternal smoking, and schooling were obtained after birth. The following data from subjects were collected at 23-25 y of age: body mass index (BMI; in kg/m(2)), physical activity, smoking, and income. Obesity was defined as a BMI >= 30. A Poisson multivariable model was performed to determine the association between cesarean delivery and BMI. Results: The obesity rate in adults born by cesarean delivery was 15.2% and in those born by vaginal delivery was 10.4% (P = 0.002). Adults born by cesarean delivery had an increased risk (prevalence ratio: 1.58; 95% CI: 1.23, 2.02) of obesity at adulthood after adjustments. Conclusion: We hypothesize that increasing rates of cesarean delivery may play a role in the obesity epidemic worldwide. Am J Clin Nutr 2011;93:1344-7. (AU)

FAPESP's process: 00/09508-7 - From perinatal health to health of the young adult: study of cohort born in 1978/79 in the hospitals of Ribeirão Preto, SP
Grantee:Marco Antonio Barbieri
Support Opportunities: Research Projects - Thematic Grants