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Understanding Wax Printing: A Simple Micropatterning Process for Paper-Based Microfluidics

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Autor(es):
Carrilho, Emanuel [1, 2] ; Martinez, Andres W. [2] ; Whitesides, George M. [2]
Número total de Autores: 3
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13566590 Sao Carlos, SP - Brazil
[2] Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 - USA
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Analytical Chemistry; v. 81, n. 16, p. 7091-7095, AUG 15 2009.
Citações Web of Science: 813
Resumo

This technical note describes a detailed study on wax printing, a simple and inexpensive method for fabricating microfluidic devices in paper using a commercially available printer and hot plate. The printer prints patterns of solid wax on the surface of the paper, and the hot plate melts the wax so that it penetrates the full thickness of the paper. This process creates complete hydrophobic barriers in paper that define hydrophilic channels, fluid reservoirs, and reaction zones. The design of each device was based on a simple equation that accounts for the spreading of molten wax in paper. (AU)