Memory in children with temporal lobe epilepsy is at least partially explained by executive dysfunction

Autor(es)

Rzezak, Patricia ^{[1, 2]} ; Guimaraes, Catarina A. ^[3] ; Fuentes, Daniel ^[4] ; Guerreiro, Marilisa M. ^[3] ; Valente, Kette D. ^{[1, 2, 5]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Ctr Interdisciplinary Res Appl Neurosci NAPNA, Sao Paulo - Brazil

^[2] Univ Sao Paulo, LIM 21, Lab Med Res 21, Neuroimaging Lab, Dept Psychiat, Sao Paulo - Brazil

^[3] Univ Campinas UNICAMP, Dept Neurol, Campinas, SP - Brazil

^[4] Univ Sao Paulo, Div Psychol & Neuropsychol, Dept Psychiat, Sao Paulo - Brazil

^[5] Univ Sao Paulo, Clin Neurophysiol Lab, Dept Psychiat, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Epilepsy & Behavior; v. 25, n. 4, p. 577-584, DEC 2012.
• Citações Web of Science: 16

Resumo

An association between memory and executive dysfunction (ED) has been demonstrated in patients with mixed neurological disorders. We aimed to investigate the impact of ED in memory tasks of children with temporal lobe epilepsy (TLE). We evaluated 36 children with TLE and 28 controls with tests for memory, learning, attention, mental flexibility, and mental tracking. Data analysis was composed of comparison between patients and controls in memory and executive function; correlation between memory and executive function tests; and comparison between patients with mild and severe ED in memory tests. Children with TLE had worse performance in focused attention, immediate and delayed recall, phonological memory, mental tracking, planning, and abstraction. Planning, abstraction, and mental tracking were correlated with visual and verbal memory. Children with severe ED had worse performance in verbal and visual memory and learning tests. This study showed that ED was related to memory performance in children with TLE. (C) 2012 Elsevier Inc. All rights reserved. (AU)

• Processo FAPESP: 05/03489-4 - Funções executivas em crianças com epilepsia do lobo temporal: correlação entre a avaliação neuropsicológica e a morfometria
• Beneficiário: Patricia Rzezak Tencer
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 03/06025-3 - Avaliação das funções executivas e mnésticas em crianças com epilepsia de lobo temporal
• Beneficiário: Patricia Rzezak Tencer
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica