A novel biomagnetic approach to study caecocolonic motility in humans

Autor(es)

Romeiro, F. G. ; Corá, L. A. ; Andreis, U. de ; Américo, M. F. ; Oliveira, R. B. ^[5] ; Baffa, O. ; Miranda, J. R. A.

• Tipo de documento: Artigo Científico
• Fonte: Neurogastroenterology and Motility; v. 18, n. 12, p. 1078-1083, Dec. 2006.
• Área do conhecimento: Ciências da Saúde - Medicina
• Assunto(s): Gastroenteropatias Processos do sistema digestório Motilidade gastrointestinal Hábitos alimentares

Resumo

Motility patterns play a major role in human colonic functions; however, its physiological significance is poorly understood. Several studies have been introducing the Alternating Current Biosusceptometry (ACB) as a valuable tool in gastroenterology and pharmaceutical research. Using gold standard techniques, great effort has been made to validate ACB as a method for measuring gastrointestinal motility in humans and animals. The aim of this study was to evaluate caecocolonic motility and its response to a meal in healthy volunteers. The results showed a dominant frequency of 3.17 ± 0.13 cycles per minute (mean ± SD) that remained unchanged even after a standardized meal (P > 0.01). The colonic response to a meal was recorded as a considerable increase in amplitude, reflected by motility index (P < 0.01) and was observed for all the volunteers. The caecocolonic motility could be assessed by the ACB providing new insights into physiological patterns of motility. Moreover, the method is non-invasive, radiation-free, cost-effective and independent of bowel preparation. (AU)

• Processo FAPESP: 05/04345-6 - Novas abordagens e aplicações de Biosusceptometria de Corrente Alternada - BAC
• Beneficiário: José Ricardo de Arruda Miranda
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 00/06338-3 - Estudo do transito de particulas nao-digeriveis no trato gastrintestinal humano pela biosusceptometria ac.
• Beneficiário: Fernando Gomes Romeiro
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica
• Processo FAPESP: 03/10107-5 - Desenvolvimento e implantação de novos métodos de estudo da acomodação e da contralidade do estômago. Aplicações em investigações da fisiologia e da fisiopatologia da motilidade (...)
• Beneficiário: Ricardo Brandt de Oliveira
• Modalidade de apoio: Auxílio à Pesquisa - Programa PRONEX - Temático