| Full text | |
| Author(s): |
Romeiro, F. G.
;
Corá, L. A.
;
Andreis, U. de
;
Américo, M. F.
;
Oliveira, R. B.
[5]
;
Baffa, O.
;
Miranda, J. R. A.
Total Authors: 7
|
| Document type: | Journal article |
| Source: | Neurogastroenterology and Motility; v. 18, n. 12, p. 1078-1083, Dec. 2006. |
| Field of knowledge: | Health Sciences - Medicine |
| Abstract | |
Motility patterns play a major role in human colonic functions; however, its physiological significance is poorly understood. Several studies have been introducing the Alternating Current Biosusceptometry (ACB) as a valuable tool in gastroenterology and pharmaceutical research. Using gold standard techniques, great effort has been made to validate ACB as a method for measuring gastrointestinal motility in humans and animals. The aim of this study was to evaluate caecocolonic motility and its response to a meal in healthy volunteers. The results showed a dominant frequency of 3.17 ± 0.13 cycles per minute (mean ± SD) that remained unchanged even after a standardized meal (P > 0.01). The colonic response to a meal was recorded as a considerable increase in amplitude, reflected by motility index (P < 0.01) and was observed for all the volunteers. The caecocolonic motility could be assessed by the ACB providing new insights into physiological patterns of motility. Moreover, the method is non-invasive, radiation-free, cost-effective and independent of bowel preparation. (AU) | |
| FAPESP's process: | 05/04345-6 - New approaches for AC Biosusceptometry |
| Grantee: | José Ricardo de Arruda Miranda |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 03/10107-5 - Development and implementation of new methods of study of the accommodation and control of the stomach. Applications in investigations of the physiology and physiopathology of motility |
| Grantee: | Ricardo Brandt de Oliveira |
| Support Opportunities: | PRONEX Research - Thematic Grants |