| Grant number: | 15/14923-9 |
| Support Opportunities: | Regular Research Grants |
| Duration: | February 01, 2016 - March 31, 2018 |
| Field of knowledge: | Biological Sciences - Biophysics - Biophysics of Processes and Systems |
| Principal Investigator: | José Ricardo de Arruda Miranda |
| Grantee: | José Ricardo de Arruda Miranda |
| Host Institution: | Instituto de Biociências (IBB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil |
Abstract
The use of noninvasive techniques, inexpensive and harmless to the individual provides a great challenge for the study of the gastrointestinal tract and other systems. Biomagnetic methods such as AC Biosusceptometry provide these advantages and include the possibility of expanding to new studies, instrumental arrangements and other biological models. The consolidation of this technique in recent years has enabled the extension of these studies to reach the pharmaceutical field, for the study of diseases in animal models, the development of new systems and more recently, detection and characterization of magnetic nanoparticles in biological systems. These approaches, unpublished pictures of nanostructured magnetic systems in the gastrointestinal tract, circulation, kidneys, liver and brain, provided by the BAC is another important aspect that we want to explore. In summary, this project envisions a multidisciplinary proposal that relates instrumentation, biophysics, pharmaceutical technology and detection and biodistribution of nanoparticles, contributing to support physiological and clinical parameters, in order to implement consistently the biomagnetic technique in different fields of study of biological systems. (AU)
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