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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Predictors of long-term survival among first-ever ischemic and hemorrhagic stroke in a Brazilian stroke cohort

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Autor(es):
Goulart, Alessandra C. [1, 2] ; Fernandes, Tiotrefis G. [3] ; Santos, Itamar S. [1] ; Alencar, Airlane P. [4] ; Bensenor, Isabela M. [1, 5] ; Lotufo, Paulo A. [1, 5]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Univ Hosp, Sao Paulo - Brazil
[2] Univ Hosp, Ctr Clin & Epidemiol Res, BR-05508009 Sao Paulo - Brazil
[3] Univ Fed Amazonas, Coari, Amazonas - Brazil
[4] Univ Sao Paulo, Inst Math & Stat, Sao Paulo - Brazil
[5] Univ Sao Paulo, Sch Med, Sao Paulo - Brazil
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: BMC Neurology; v. 13, MAY 24 2013.
Citações Web of Science: 13
Resumo

Background: Few studies have examined both ischemic and hemorrhagic stroke to identify prognostic factors associated to long-term stroke survival. We investigated long-term survival and predictors that could adversely influence ischemic and hemorrhagic first-ever stroke prognosis. Methods: We prospectively ascertained 665 consecutive first-ever ischemic and hemorrhagic stroke cases from ``The Study of Stroke Mortality and Morbidity{''} (The EMMA Study) in a community hospital in Sao Paulo, Brazil. We evaluated cardiovascular risk factors and sociodemographic characteristics (age, gender, race and educational level). Results: We found a lower survival rate among hemorrhagic cases compared to ischemic stroke cases at the end of 4 years of follow-up (52% vs. 44%, p = 0.04). The risk of death was two times higher among people with ischemic stroke without formal education. Also, we found consistently higher risk of death for diabetics with ischemic stroke (HR = 1.45; 95% CI = 1.07-1.97) compared to no diabetics. As expected, age equally influenced on the high risk of poor survival, regardless of stroke subtype. Conclusions: For ischemic stroke, the lack of formal education and diabetes were significant independent predictors of poor long-term survival. (AU)

Processo FAPESP: 11/17568-4 - Vigilância epidemiológica da doença cerebrovascular: perfil de risco associado à letalidade precoce e a longo prazo no estudo de mortalidade e morbidade do acidente vascular cerebral (Estudo EMMA), São Paulo-Brasil
Beneficiário:Alessandra Carvalho Goulart
Modalidade de apoio: Auxílio à Pesquisa - Regular