Antioxidant quinonemethide triterpenes from Salacia campestris

Autor(es)

Carvalho, Paulo R. F. ; Silva, Dulce H. S. ; Bolzani, Vanderlan S. ; Furlan, Maysa ^[4]

• Tipo de documento: Artigo Científico
• Fonte: Chemistry and Biodiversity; v. 2, n. 3, p. 367-372, Mar. 2005.
• Área do conhecimento: Ciências Exatas e da Terra - Química
• Assunto(s): Triterpenos Salacia Antioxidantes

Resumo

A new quinonemethide triterpene named as salacin, has been isolated from the root bark of Salacia campestris in addition to the known pristimerin, maytenin, 20 alpha-hydroxymaytenin, and netzahualcoyene. Salacin was identified on the basis of NMR-spectral and mass spectrometric analysis. The free-radical scavenging activities of the quinonemethide triterpenes salacin (1), pristimerin (2), maytenin (3), 20 alpha-hydroxymaytenin (4), and netzahualcoyene (5) towards DPPH have been evaluated and showed absorbance variation (ÄA) of 19, 20, 39, 28, 55, and 10%, respectively, having rutin (74% at 50 ìM) and BHT (7% at 50 ìM) as standard compounds. (AU)

• Processo FAPESP: 97/10184-7 - Estudo quimico e biossintetico em especies de celastraceae e hippocrateaceae.
• Beneficiário: Maysa Furlan
• Modalidade de apoio: Auxílio à Pesquisa - Regular