Antioxidant quinonemethide triterpenes from Salacia campestris

Carvalho, Paulo R. F.; Silva, Dulce H. S.; Bolzani, Vanderlan S.; Furlan, Maysa

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Antioxidant quinonemethide triterpenes from Salacia campestris

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Author(s):	Carvalho, Paulo R. F. ; Silva, Dulce H. S. ; Bolzani, Vanderlan S. ; Furlan, Maysa ^[4] Total Authors: 4
Document type:	Journal article
Source:	Chemistry and Biodiversity; v. 2, n. 3, p. 367-372, Mar. 2005.
Field of knowledge:	Physical Sciences and Mathematics - Chemistry
Abstract
A new quinonemethide triterpene named as salacin, has been isolated from the root bark of Salacia campestris in addition to the known pristimerin, maytenin, 20 alpha-hydroxymaytenin, and netzahualcoyene. Salacin was identified on the basis of NMR-spectral and mass spectrometric analysis. The free-radical scavenging activities of the quinonemethide triterpenes salacin (1), pristimerin (2), maytenin (3), 20 alpha-hydroxymaytenin (4), and netzahualcoyene (5) towards DPPH have been evaluated and showed absorbance variation (ÄA) of 19, 20, 39, 28, 55, and 10%, respectively, having rutin (74% at 50 ìM) and BHT (7% at 50 ìM) as standard compounds. (AU)

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