Antioxidant phenolic and quinonemethide triterpenes from Cheiloclinium cognatum

Autor(es)

Jeller, Alex Haroldo ; Silva, Dulce Helena Siqueira ; Lião, Luciano Morais ; Bolzani, Vanderlan da Silva ; Furlan, Maysa ^[5]

• Tipo de documento: Artigo Científico
• Fonte: Phytochemistry; v. 65, n. 13, p. 1977-1982, July 2004.
• Área do conhecimento: Ciências Exatas e da Terra - Química
• Assunto(s): Antioxidantes Hippocrateaceae Triterpenos Compostos fenólicos

Resumo

The triterpenes, 22betha-hydroxypristimerin and cognatine, were isolated together with the known compounds pristimerin, maytenin, 20alpha-hydroxymaytenin, 22betha-hydroxymaytenin, netzahualcoyol, netzahualcoyondiol and netzahualcoyone from root bark of Cheiloclinium cognatum. The structures of the isolated compounds were elucidated by interpretation of their spectral data, including gHMQC and gHMBC experiments.The isolates were investigated for their radical scavenging abilities through a spectrophotometric assay involving reduction of 2, 2-diphenyl-picryl hydrazyl (DPPH). The triterpenes, 22betha-hydroxypristimerin and cognatine, were isolated together with seven known compounds from Cheiloclinium cognatum. The isolates were investigated for their radical scavenging abilities. (AU)

• Processo FAPESP: 97/10184-7 - Estudo quimico e biossintetico em especies de celastraceae e hippocrateaceae.
• Beneficiário: Maysa Furlan
• Modalidade de apoio: Auxílio à Pesquisa - Regular