Antioxidant phenolic and quinonemethide triterpenes from Cheiloclinium cognatum

Jeller, Alex Haroldo; Silva, Dulce Helena Siqueira; Lião, Luciano Morais; Bolzani, Vanderlan da Silva; Furlan, Maysa

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Antioxidant phenolic and quinonemethide triterpenes from Cheiloclinium cognatum

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Author(s):	Jeller, Alex Haroldo ; Silva, Dulce Helena Siqueira ; Lião, Luciano Morais ; Bolzani, Vanderlan da Silva ; Furlan, Maysa ^[5] Total Authors: 5
Document type:	Journal article
Source:	Phytochemistry; v. 65, n. 13, p. 1977-1982, July 2004.
Field of knowledge:	Physical Sciences and Mathematics - Chemistry
Abstract
The triterpenes, 22betha-hydroxypristimerin and cognatine, were isolated together with the known compounds pristimerin, maytenin, 20alpha-hydroxymaytenin, 22betha-hydroxymaytenin, netzahualcoyol, netzahualcoyondiol and netzahualcoyone from root bark of Cheiloclinium cognatum. The structures of the isolated compounds were elucidated by interpretation of their spectral data, including gHMQC and gHMBC experiments.The isolates were investigated for their radical scavenging abilities through a spectrophotometric assay involving reduction of 2, 2-diphenyl-picryl hydrazyl (DPPH). The triterpenes, 22betha-hydroxypristimerin and cognatine, were isolated together with seven known compounds from Cheiloclinium cognatum. The isolates were investigated for their radical scavenging abilities. (AU)

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