Phase behavior and process parameters effect on grape seed extract encapsulation by SEDS technique

Autor(es)

Boschetto, Daiane L. ^[1] ; Dalmolin, Irede ^[2] ; de Cesaro, Alana M. ^[3] ; Rigo, Aline A. ^[3] ; Ferreira, Sandra R. S. ^[1] ; Meireles, M. Angela A. ^[2] ; Batista, Eduardo A. C. ^[2] ; Vladimir Oliveira, J. ^[1]

Afiliação do(s) autor(es)

^[1] Univ Fed Santa Catarina, Dept Chem & Food Engn, BR-88040900 Florianopolis, SC - Brazil

^[2] Univ Estadual Campinas, Sch Food Engn, Dept Food Engn, BR-13083862 Campinas, SP - Brazil

^[3] Univ Reg Integrada Alto Uruguai & Missoes, Dept Food Engn, BR-99700000 Erechim, RS - Brazil

• Tipo de documento: Artigo Científico
• Fonte: INDUSTRIAL CROPS AND PRODUCTS; v. 50, p. 352-360, OCT 2013.
• Citações Web of Science: 18

Resumo

Grape seed extract (GSE) was encapsulated in biocompatible poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) using the solution enhanced dispersion by supercritical fluids (SEDS) technique. In order to help selecting the appropriate operating conditions for the encapsulation mechanism, the fluid phase behavior of pseudo-ternary carbon dioxide (CO2) + dichloromethane (DCM)+GSE systems was studied employing a static synthetic method. The investigated SEDS operating parameters were in the following range: pressure (8-12 MPa), temperature (308-318K), GSE to PHBV mass ratio (1:1-1:3), with concentrations of organic solution formed by GSE (6.67-20.00 kg m(-3)) in DCM, and fixed PHBV 20.00 kg m(-3) in DCM. The organic solution flow rate was fixed at 1.67 x 10(-8) m(3) s(-1) and the antisolvent flow rate at 3.33 x 10(-7) m(3) s(-1). The effect of operating parameters on particle size, particle morphology and encapsulation efficiency was checked. The best result was obtained at 8 MPa, 308K, GSE to PHBV mass ratio of 1:1, with concentration of GSE and PHBV, both of 20.00 kg m(-3), leading to spherical particles with the smallest size of similar to 0.70 mu m and encapsulation efficiency of 66.01%. SEM-EDS micrographs showed that, besides spherical particles, agglomerated particles were observed at temperatures higher than 308 K, which might be due to a more favorable extract re-dissolution at higher temperatures. (C) 2013 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 08/56258-8 - Phase equilibrium and purification processes in the production of biofuels and biocompounds
• Beneficiário: Antonio José de Almeida Meirelles
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOEN - Temático