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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Clinical, cytologic, and histologic features of a mammary micropapillary carcinoma in a dog

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Autor(es):
Salgado, Breno S. [1] ; Monteiro, Lidianne N. [1] ; Colodel, Marcia M. [2] ; Figueiroa, Fernanda C. [2] ; Soares, Luisa M. [2] ; Nonogaki, Suely [3] ; Rocha, Rafael M. [3] ; Rocha, Noeme S. [1, 2]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Univ Estadual Paulista UNESP, Dept Patol, Fac Med Botucatu, Botucatu, SP - Brazil
[2] Univ Estadual Paulista UNESP, Dept Clin Vet, Fac Med Vet & Zootecnia, Botucatu, SP - Brazil
[3] Hosp AC Camargo Fund Antonio Prudente, Fundacao Antonio Prudente, Dept Anat Patol, Sao Paulo - Brazil
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: VETERINARY CLINICAL PATHOLOGY; v. 42, n. 3, p. 382-385, SEP 2013.
Citações Web of Science: 1
Resumo

Mammary invasive micropapillary carcinoma is a rare variant of mammary carcinoma that was recently recognized in dogs. The cytologic features and biologic behavior of such neoplasms in dogs have not yet been widely discussed in the veterinary literature. We report the clinical, cytologic, and histologic features of a canine micropapillary carcinoma in a 13-year-old female mongrel dog. The mammary region presented with extreme local pain, severe edema and erythema, and multifocal epidermal ulceration, which is typical for an inflammatory mammary carcinoma. Fine-needle aspirates were highly cellular and consisted of individual cells and papillary cell clusters with characteristics of malignant epithelial cells. Histologic examination revealed neoplastic cells arranged in small papillae without fibrovascular cores, sometimes inside clear lymphatic spaces, indicating lymphovascular invasion. Regional lymph node evaluation revealed metastatic cells. Due to deteriorating clinical condition the dog was euthanatized 5months after mastectomy. At necropsy, metastatic neoplastic mammary cells were found in popliteal and mediastinal lymph nodes, the right femoral biceps muscle, liver, heart, lungs, and urinary bladder. (AU)

Processo FAPESP: 09/52748-3 - Associação entre os níveis de resíduos piretróides e graus de agressividade dos carcinomas mamários espontâneos de cadelas
Beneficiário:Marcia Moleta Colodel
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 10/51596-2 - Análise da imunoexpressão de S100A4 e osteopontina nos carcinomas mamários esporádicos de cadelas
Beneficiário:Noeme Sousa Rocha
Linha de fomento: Auxílio à Pesquisa - Regular