Recombinants proteins for industrial uses: utilization of Pichia pastoris expression system

Autor(es)

Rabert, Claudia ^{[1, 2]} ; Weinacker, Daniel ^{[3, 1]} ; Pessoa, Jr., Adalberto ^[3] ; Farias, Jorge G. ^[1]

Afiliação do(s) autor(es)

^[1] Univ La Frontera, Fac Ingn Ciencias & Adm, Dept Ingn Quim, Temuco - Chile

^[2] Univ La Frontera, Fac Ciencias Agr & Forestales, Dept Prod Agr, Temuco - Chile

^[3] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Tecnol Bioquim Farmaceut, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Brazilian Journal of Microbiology; v. 44, n. 2, p. 351-356, 2013.
• Citações Web of Science: 15

Resumo

The innovation in industrial process with impact in the efficient production is the major challenge for actual industry. A high numerous of enzymes are utilized in at different level of process; the search for new alternatives with better characteristic has become a field of study of great interest, the recombinant protein achievement in a different host system is an alternative widely assessed for production of this. The microorganism Pichia pastoris has been used like a successful expression system in diverse areas, improved the yield and extraction-recovery of the product expressed. The reported of diverse authors in the production of enzymes with different application in industry is varied, in this review the different industry areas and the characteristic of the enzymes produced are detailed. (AU)

• Processo FAPESP: 12/50210-9 - Produção de fragmentos recombinantes de anticorpos a partir do cultivo de Pichia pastoris geneticamente modificada
• Beneficiário: Adalberto Pessoa Junior
• Modalidade de apoio: Auxílio à Pesquisa - Regular