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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Salivary carriage of periodontal pathogens in generalized aggressive periodontitis families

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Autor(es):
Monteiro, Mabelle Freitas [1] ; Casati, Marcio Zaffalon [1] ; Taiete, Tiago [1] ; Sallum, Enilson Antonio [1] ; Nociti-, Jr., Francisco Humberto [1] ; Ruiz, Karina Gonzales [1] ; Viana Casarin, Renato Correa [1, 2]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Sch Dent Piracicaba, Dept Prosthodont & Periodont, Piracicaba - Brazil
[2] Univ Estadual Paulista, Dept Periodont, UNIP, Sao Paulo - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: International Journal of Paediatric Dentistry; v. 24, n. 2, p. 113-121, MAR 2014.
Citações Web of Science: 3
Resumo

BackgroundGeneralized aggressive periodontitis (GAP) is a multifactorial disease that shows a specific microbial profile and a familial aggregation. AimThis study evaluated the salivary microbial profile of families with a history of GAP and compared them with healthy families. DesignFifteen families with parents presenting periodontal health and 15 with parents with a history of GAP were selected. Each family had a child aged 6-12years. Stimulated saliva was collected from all subjects, and Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), and Aggregatibacter actinomycetemcomitans (Aa) amounts were determined. ResultsChildren of GAP families showed higher detection of Aa (90%) than children of healthy families (45%) (P<0.05). Parents with GAP showed a Pg salivary concentration statistically higher than that of healthy parents (P<0.05).Children of GAP families, however, exhibited similar Pg concentration than healthy children (P>0.05). Tf amounts did not differ either in parents or in children (P>0.05) The infection risk calculation indicates that children who have one parent who is positive for Aa have 16.3 times (95% CI 3.1-87.2) more risk of being infected with Aa (P<0.05) than children from an Aa-negative family. ConclusionIt may be concluded that children of parents with aggressive periodontitis have higher levels and higher risk of Aa infection. (AU)

Processo FAPESP: 10/19150-4 - Avaliação da transmissibilidade de patógenos periodontais em familiares de indivíduos portadores de periodontite agressiva generalizada.
Beneficiário:Mabelle de Freitas Monteiro
Modalidade de apoio: Bolsas no Brasil - Iniciação Científica