A simple method to synthesize fluorescent modified gold nanoparticles using tryptamine as the reducing and capping agent

Autor(es)

de Carvalho, Marcos Alberto ^[1] ; Andrade, Patricia Fernanda ^[1] ; Andrade Corbi, Fabiana Cristina ^[1] ; Goncalves, Maria do Carmo ^[1] ; Formiga, Andre Luiz Barboza ^[1] ; Mazali, Italo Odone ^[1] ; Bonacin, Juliano Alves ^[1] ; Corbi, Pedro Paulo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Campinas UNICAMP, Inst Chem, BR-13083970 Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Synthetic Metals; v. 185, p. 61-65, DEC 1 2013.
• Citações Web of Science: 1

Resumo

A simple method to synthesize fluorescent modified gold nanoparticles using tryptamine as the reducing and capping agent is described. The presented method produces gold nanoparticles with 36.65 +/- 5.30 nm average size. The modified gold nanoparticles were characterized by elemental and thermal analyses, dynamic light scattering, transmission electron microscopy, zeta potential, X-ray powder diffraction and spectroscopic techniques, such as electronic spectroscopy in ultraviolet-visible and fluorescence excitation-emission. In addition, modified gold nanoparticles were analyzed by solid state N-15 nuclear magnetic resonance spectroscopy, which confirmed the coordination of tryptamine on the gold nanoparticles surface. A prominent characteristic observed is the fluorescence of tryptamine which was not quenched after the coordination to gold nanoparticles. The results presented in this paper confirm the modification of gold nanoparticles by tryptamine and suggest potential use of such nanoparticles as labeling dye in biological systems. (C) 2013 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 12/08230-2 - Síntese, caracterização e estudo das atividades farmacológicas de complexos metálicos de Ag(I), Au(I), Pt(II) e Pd(II) com ligantes bioativos
• Beneficiário: Pedro Paulo Corbi
• Modalidade de apoio: Auxílio à Pesquisa - Regular