Effect of natural gel product on bovine dentin erosion in vitro

Autor(es)

Sales-Peres, Andre de Carvalho ^[1] ; Marsicano, Juliane Avansini ^[1] ; Garcia, Rudan Paraiso ^[1] ; Forim, Moacir Rossi ^[2] ; Fernandes da Silva, Maria Fatima das Gracas ^[2] ; de Carvalho Sales-Peres, Silvia Helena ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Bauru Sch Dent, Dept Pediat Dent Orthodont & Community Hlth, BR-17012901 Bauru, SP - Brazil

^[2] Univ Fed Sao Carlos, Lab Nat Prod, Dept Chem, BR-13560 Sao Carlos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Journal of Applied Oral Science; v. 21, n. 6, p. 597-600, NOV-DEC 2013.
• Citações Web of Science: 1

Resumo

Objective: To evaluate the efficacy of Neem (Azadirachta indica) experimental gel for the prevention of erosive wear on bovine dentin, in vitro. Material and Methods: One hundred dentin blocks were allocated into 5 experimental groups (20 samples each): C (control group, without gel); CG (control group, only base gel); F (fluoride gel, 1.23% NaF; pH 4.1, Dentsply; Brazil); N (Neem gel, 10% neem extract; pH 4.1, manipulation); NF (Neem+fluoride gel, 10% Neem extract and 1.23% NaF; pH 4.1, manipulation). The blocks were stored in artificial saliva for 24 hours. After this, they were submitted to six alternating re- and demineralization cycles. The blocks were analyzed for wear (profilometry). The results were submitted to statistical analysis by ANOVA and Tukey tests (P<0.05). Results: The mean wear (±SD, µm) was shown as follows in groups: C (13.09±0.99), CG (10.60±1.99), F (10.90±1.44), N (12.68±1.13) and NF (10.84±1.65). All gels showed some preventive action when compared with control group. However, significant differences were found only between Neem+fluoride gel and fluoride gel. Conclusion: A single application of a neem-containing fluoride gel reduced dentin erosion, thus it is a possible alternative in reducing dental wear. Further research should investigate the action mechanism and the synergism between them. (AU)

• Processo FAPESP: 08/10922-4 - Efeito do gel de NIM em dentina bovina submetida ao desafio erosivo in vitro
• Beneficiário: Rudan Paraiso Garcia
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica