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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of natural gel product on bovine dentin erosion in vitro

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Author(s):
Sales-Peres, Andre de Carvalho [1] ; Marsicano, Juliane Avansini [1] ; Garcia, Rudan Paraiso [1] ; Forim, Moacir Rossi [2] ; Fernandes da Silva, Maria Fatima das Gracas [2] ; de Carvalho Sales-Peres, Silvia Helena [1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Bauru Sch Dent, Dept Pediat Dent Orthodont & Community Hlth, BR-17012901 Bauru, SP - Brazil
[2] Univ Fed Sao Carlos, Lab Nat Prod, Dept Chem, BR-13560 Sao Carlos, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Journal of Applied Oral Science; v. 21, n. 6, p. 597-600, NOV-DEC 2013.
Web of Science Citations: 1
Abstract

Objective: To evaluate the efficacy of Neem (Azadirachta indica) experimental gel for the prevention of erosive wear on bovine dentin, in vitro. Material and Methods: One hundred dentin blocks were allocated into 5 experimental groups (20 samples each): C (control group, without gel); CG (control group, only base gel); F (fluoride gel, 1.23% NaF; pH 4.1, Dentsply; Brazil); N (Neem gel, 10% neem extract; pH 4.1, manipulation); NF (Neem+fluoride gel, 10% Neem extract and 1.23% NaF; pH 4.1, manipulation). The blocks were stored in artificial saliva for 24 hours. After this, they were submitted to six alternating re- and demineralization cycles. The blocks were analyzed for wear (profilometry). The results were submitted to statistical analysis by ANOVA and Tukey tests (P<0.05). Results: The mean wear (±SD, µm) was shown as follows in groups: C (13.09±0.99), CG (10.60±1.99), F (10.90±1.44), N (12.68±1.13) and NF (10.84±1.65). All gels showed some preventive action when compared with control group. However, significant differences were found only between Neem+fluoride gel and fluoride gel. Conclusion: A single application of a neem-containing fluoride gel reduced dentin erosion, thus it is a possible alternative in reducing dental wear. Further research should investigate the action mechanism and the synergism between them. (AU)

FAPESP's process: 08/10922-4 - Effect of the neem gel in bovine dentine submitted to the erosive challenge in vitro
Grantee:Rudan Paraiso Garcia
Support Opportunities: Scholarships in Brazil - Scientific Initiation