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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Discrimination of bile acids by the rainbow trout olfactory system: Evidence as potential pheromone

Autor(es):
Giaquinto, Percilia C. [1] ; Hara, Toshiaki J. [2]
Número total de Autores: 2
Afiliação do(s) autor(es):
[1] Univ Estadual Paulista. Inst Biol
[2] Fisheries & Oceans Canada. Inst Freshwater
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: Biological Research; v. 41, n. 1, p. 33-42, 2008.
Citações Web of Science: 18
Resumo

Electro-olfactogram recording was used to determine whether the olfactory epithelium of adult rainbow trout is specifically sensitive to bile acids, some of which have been hypothesized to function as pheromones. Of 38 bile acids that had been pre-screened for olfactory activity, 6 were selected. The rainbow trout-specific bile acids, taurocholic acid (TCA), and taurolithocholic acid 3-sulfate (TLS) were the most potent compounds tested. TLS had a distinctive dose-response curve. Cross-adaptation experiments demonstrated that sensitivity to bile acids is attributable to at least 3 independent classes of olfactory receptor sites. Our data suggest that bile acids are discriminated by olfaction in rainbow trout, supporting the possibility that these compounds function as pheromones. (AU)

Processo FAPESP: 02/01333-9 - Sinalizações de alarme no sistema predador-presa em pintado (Pseudoplatystoma coruscans): estudos comportamentais, neurofisiológicos e neuroanatômicos
Beneficiário:Percilia Cardoso Giaquinto
Linha de fomento: Bolsas no Brasil - Pós-Doutorado