Lower serum IgA levels in horses kept under intensive sanitary management and physical training

Autor(es)

Souza, C. M. ^[1] ; Miotto, B. A. ^[2] ; Bonin, C. P. ^[3] ; Camargo, M. M. ^[4]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo. Inst Biomed Sci

^[2] Univ Sao Paulo. Inst Biomed Sci

^[3] Univ Sao Paulo. Inst Biomed Sci

^[4] Univ Sao Paulo. Inst Biomed Sci

• Tipo de documento: Artigo Científico
• Fonte: ANIMAL; v. 4, n. 12, p. 2080-2083, DEC 2010.
• Citações Web of Science: 0

Resumo

Quantity and variety of environmental antigens, age, diet, vaccine protocols, exercising practice and mucosal cytokine microenvironment are factors that influence serum immunoglobulin (Ig) levels. IgA, IgG, IgG(T) and IgM were quantified in 60 horses, which were classified into two groups, `intensive' or `relaxed', according to sanitary standards of the facilities and physical exercise to which animals were subjected to. The `intensive' group presented lower means for all isotypes, but only IgA presented a significant (P < 0.0064) difference when compared to the `relaxed' group. This suggests that mucosal immunity found in the `intensive' group is lower when compared to the `relaxed' group. Our data suggest that athlete horses may be less poised to mount an effective mucosal immunity response to environmental challenges and should not be considered by the same perspectives as a free-ranging horse. (AU)

• Processo FAPESP: 06/50543-7 - Ocorrencia de deficiencia seletiva de igm (sigmd) em equinos no brasil e o papel dos receptores do tipo toll (tlr).
• Beneficiário: Maristela Martins de Camargo
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 08/54811-1 - Regulacao da sinalizacao por lps em linfocitos b de equinos.
• Beneficiário: Maristela Martins de Camargo
• Modalidade de apoio: Auxílio à Pesquisa - Regular