Effects of different sleep deprivation protocols on sleep perception in healthy volunteers

Autor(es)

Goulart, Leonardo I. ^[1] ; Pinto, Jr., Luciano R. ^[2] ; Perlis, Michael L. ^[3] ; Martins, Raquel ^[2] ; Caboclo, Luis Otavio ^[1] ; Tufik, Sergio ^[2] ; Andersen, Monica L. ^[2]

Afiliação do(s) autor(es)

^[1] Hosp Israelita Albert Einstein, Dept Neurofisiol Clin, BR-05652900 Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Dept Psicobiol, Sao Paulo - Brazil

^[3] Univ Penn, Sch Med, Dept Psychiat, Behav Sleep Med Program, Philadelphia, PA 19104 - USA

• Tipo de documento: Artigo Científico
• Fonte: Sleep Medicine; v. 15, n. 10, p. 1219-1224, OCT 2014.
• Citações Web of Science: 6

Resumo

Objectives: To investigate whether different protocols of sleep deprivation modify sleep perception. Methods: The effects of total sleep deprivation (TD) and selective rapid eye movement (REM) sleep deprivation (RD) on sleep perception were analyzed in normal volunteers. Thirty- one healthy males with normal sleep were randomized to one of three conditions: (i) normal uninterrupted sleep; (ii) four nights of RD; or (iii) two nights of TD. Morning perception of total sleep time was evaluated for each condition. Sleep perception was estimated using total sleep time (in hours) as perceived by the volunteer divided by the total sleep time (in hours) measured by polysomnography (PSG). The final value of this calculation was defined as the perception index (PI). Results: There were no significant differences among the three groups of volunteers in the total sleep time measured by PSG or in the perception of total sleep time at baseline condition. Volunteers submitted to RD exhibited lower sleep PI scores as compared with controls during the sleep deprivation period (P < 0.05). Both RD and TD groups showed PI similar to controls during the recovery period. Conclusion: Selective REM sleep deprivation reduced the ability of healthy young volunteers to perceive their total sleep time when compared with time measured by PSG. The data reinforce the influence of sleep deprivation on sleep perception. (C) 2014 Elsevier B. V. All rights reserved. (AU)

• Processo FAPESP: 06/58276-8 - Avaliação da densidade do transportador dopaminérgico utilizando [99mtc]-trodat e SPECT após privação de sono
• Beneficiário: Raquel Cristina Martins da Silva
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 98/14303-3 - Center for Sleep Studies
• Beneficiário: Sergio Tufik
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs