Development and characterization of solid lipid microparticles loaded with ascorbic acid and produced by spray congealing

Autor(es)

Matos-, Jr., Fernando Eustaquio ^[1] ; Di Sabatino, Marcello ^[2] ; Passerini, Nadia ^[2] ; Favaro-Trindade, Carmen Silvia ^[1] ; Albertini, Beatrice ^[2]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Coll Anim Sci & Food Engn, BR-13535900 Sao Paulo - Brazil

^[2] Univ Bologna, Dept Pharm & Biotechnol, I-40127 Bologna - Italy

• Tipo de documento: Artigo Científico
• Fonte: Food Research International; v. 67, p. 52-59, JAN 2015.
• Citações Web of Science: 16

Resumo

The aim of this work was to produce solid lipid microparticles loaded with ascorbic acid (AA). The microparticles were produced using spray congealing technique with a theoretical AA loading of 15, 25 or 40% (w/w). Fully hydrogenated palm oil and vegetable glycerol monostearate were used as carriers. The microparticles were characterized in terms of yield, morphology (SEM), mean size, size distribution, thermal behavior (DSC), encapsulation efficiency and stability of AA. The microparticles were spherical, the process yield was over 81% and the encapsulation efficiency ranged from 74 to 84%. The stability of the encapsulated AA was over 75% after 56 days of storage. The type of carrier, the AA concentration and the storage temperature did not significantly influence the stability. In conclusion microencapsulation by spray congealing is an important alternative to ensure AA stability, even at temperatures higher than those commonly used in food storage. (C) 2014 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 12/01907-7 - Desenvolvimento e caracterização de micropartículas carregadas com ácido ascórbico obtidas por spray congealing
• Beneficiário: Fernando Eustáquio de Matos Junior
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Mestrado
• Processo FAPESP: 10/13117-5 - Desenvolvimento, caracterização e aplicação de microcápsulas de ácido ascórbico obtidas por spray chilling
• Beneficiário: Fernando Eustáquio de Matos Junior
• Modalidade de apoio: Bolsas no Brasil - Mestrado