Sleep disorders in patients with myasthenia gravis: a systematic review

Autor(es):Mostrar menos -

Oliveira, Ezequiel Fernandes ^[1] ; Nacif, Sergio R. ^[1] ; Pereira, Nixon Alves ^[1] ; Fonseca, Nina Teixeira ^[1] ; Urbano, Jessica Julioti ^[1] ; Perez, Eduardo Araujo ^[1] ; Cavalcante, Valeria ^[2] ; Oliveira, Claudia Santos ^[1] ; Insalaco, Giuseppe ^[3] ; Oliveira, Acary Sousa Bulle ^[2] ; Franco Oliveira, Luis Vicente ^[1]

Afiliação do(s) autor(es)

^[1] Nove de Julho Univ, UNINOVE, Sleep Lab, Rehabil Sci Masters & PhD Degree Program, Sao Paulo, SP - Brazil

^[2] Fed Univ Sao Paulo UNIFESP, Dept Neurol & Neurosurg, Div Neuromuscular Disorders, Sao Paulo - Brazil

^[3] Natl Res Council Italy, Inst Biomed & Mol Immunol A Monroy, Rome - Italy

• Tipo de documento: Artigo de Revisão
• Fonte: Journal of Physical Therapy Science; v. 27, n. 6, p. 2013-2018, JUN 2015.
• Citações Web of Science: 6

Resumo

{[}Purpose] This systematic review evaluated the presence of sleep-disordered breathing in patients with myasthenia gravis and clarified the role of physiotherapy. {[}Subjects and Methods] We followed the PRISMA declaration criteria. The evaluation was performed in accordance with the STROBE statement for observational and cross-sectional studies and the CONSORT checklist for clinical trials. Searches were followed by hand on MEDLINE, EMBASE, SciELO, PubMed Central, and the Cochrane Central Register of Controlled Trials. {[}Results] Our searches yielded a total of 36 studies published between 1970 and 2014. The number of patients involved ranged from 9-490. Of the 36 studies, 19 articles were excluded because they did not meet the inclusion criteria. Therefore, 17 observational, cross-sectional, or clinical studies assessing the quality of sleep and prevalence of sleep disorders in patients with myasthenia gravis were eligible for our review. {[}Conclusion] Some studies of patients with MG show that patients with MG are associated with poor sleep quality, excessive daytime sleepiness, presence of restless syndrome, and a higher incidence of SDB, while other studies do not report such associations. Therefore, given the current inconclusive evidence and limited literature, further study of sleep disturbances in patients with MG is needed. (AU)

• Processo FAPESP: 14/07262-3 - Efeito da hemodiálise na colapsabilidade das vias aéreas superiores em pacientes com doença renal crônica
• Beneficiário: Nina Teixeira Fonsêca
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 13/21765-5 - Resistência e complacência de pulmões durante o processo de descelularização e recelularização com células-tronco
• Beneficiário: Nadua Apostólico
• Modalidade de apoio: Bolsas no Brasil - Mestrado