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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Combined Training Reduces Subclinical Inflammation in Obese Middle-Age Men

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Autor(es):
Brunelli, Diego T. [1] ; Chacon-Mikahil, Mara Patricia T. [1] ; Gaspari, Arthur F. [1] ; Lopes, Wendell Arthur [1, 2] ; Bonganha, Valeria [1] ; Bonfante, Ivan Luiz P. [1] ; Bellotto, Maria Luisa [3] ; Libardi, Cleiton Augusto [4] ; Cavaglieri, Claudia Regina [1]
Número total de Autores: 9
Afiliação do(s) autor(es):
[1] Univ Campinas UNICAMP, Fac Phys Educ, Exercise Physiol Lab FISEX, Campinas, SP - Brazil
[2] State Univ Maringa UEM, Dept Phys Educ, Maringa, Parana - Brazil
[3] Integrated Metropolitan Coll Campinas METROCAMP, Campinas, SP - Brazil
[4] Fed Univ Sao Carlos UFSCar, Ctr Biol & Hlth Sci CCBS, Dept Phys Educ DEFMH, Sao Carlos, SP - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE; v. 47, n. 10, p. 2207-2215, OCT 2015.
Citações Web of Science: 13
Assunto(s):Obesidade   Citocinas   Adipocinas   Resistência à insulina   Treinamento físico
Resumo

Purpose: We investigated the effects of 24 wk of combined training on proinflammatory and anti-inflammatory markers associated with obesity in obese middle-age men. Methods: Thirty obese men (48.73 1.04 yr; body mass index, 31.00 0.29 kgm(-2)) underwent 24 wk of combined training {[}CT (N = 17), aerobic (50%-85% of (V) over dot(2peak)) and resistance (6-10 maximum repetition {[}RM]) training)] three times per week, 60 min per session, or a control group (N = 13). Anthropometric measures, maximal strength for leg press and bench press, peak oxygen uptake ((V) over dotO(2peak)) and serum concentrations of C-reactive protein (CRP), tumor necrosis factor (TNF-), interleukin-6 (IL-6), IL-10, IL-15, resistin, leptin, and adiponectin were determined before (M1) and after 8 (M2), 16 (M3), and 24 (M4) wk of the experimental design. Results: Significant increases were observed in the maximal strength for bench press and leg press, (V) over dotO(2peak), and serum concentrations of adiponectin and IL-15 for CT. Concomitantly, significant decreases were observed in percentage body fat and serum concentrations of CRP, resistin, and leptin for CT after the experimental period. Conclusion: Twenty-four weeks of moderate- to high-intensity CT reduced markers of subclinical inflammation associated with obesity and improved insulin resistance and functional capabilities of obese middle-age men, regardless of dietary intervention and weight loss. (AU)

Processo FAPESP: 11/09446-6 - Efeitos do treinamento concorrente sobre as respostas inflamatórias e morfofuncionais em homens obesos de meia idade
Beneficiário:Claudia Regina Cavaglieri
Modalidade de apoio: Auxílio à Pesquisa - Regular