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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

The relationship between anemia, hemoglobin concentration and frailty in Brazilian older adults

Texto completo
Autor(es):
Corona, Ligiana Pires [1] ; Andrade, F. C. Drumond [2] ; de Oliveira Duarte, Y. A. [3] ; Lebrao, M. L. [4]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Estadual Campinas, Fac Sci Appl, BR-13484350 Limeira, SP - Brazil
[2] Univ Illinois, Dept Kinesiol & Community Hlth, Urbana, IL - USA
[3] Univ Sao Paulo, Sch Nursing, Dept Med Surg Nursing, Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Epidemiol, Fac Publ Hlth, Sao Paulo - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: Journal of Nutrition Health & Aging; v. 19, n. 9, p. 935-940, NOV 2015.
Citações Web of Science: 11
Resumo

to explore the relationship between anemia, hemoglobin concentration and frailty syndrome in older adults. This was a cross-sectional population-based study, with adults a parts per thousand yen60 years (n=1,256) from the third wave of the SABE Cohort Study (Health, Well-being and Aging) conducted in 2010 in So Paulo, Brazil. Frailty syndrome was evaluated according to FriedA ` s phenotype. Anemia was defined using the WHO criteria (hemoglobin concentration < 12 g/dL for women and < 13 g/dL for men). Four approaches were used to verify the associations between anemia, hemoglobin concentration and frailty status or number of frailty criteria. We used logistic regression and Poisson regression in the analyses, and they were adjusted in three hierarchical models using three blocks of variables: basic characteristics; clinical characteristics; cognitive status. Mean hemoglobin concentration was significantly lower in frail elderly (13.3g/dL, versus 14.3g/dL in non-frail; p < 0.001). Prevalence of anemia was also significantly higher in frail when compared to non-frail elderly (24.2% and 3.8%; p < 0.001). Anemia was significantly associated to low physical activity, weakness and slowness. In the fully adjusted regression models, anemia was strongly associated to frailty (OR=3.27, 95%IC=1.89,5.65; p < 0.001), and lower levels of hemoglobin were associated to higher number of frailty criteria. We found important associations between anemia, hemoglobin concentration and frailty; anemic older adults were more likely to be frail, and lower levels of hemoglobin were associated to higher number of frailty criteria showing a clear dose-response effect.. (AU)

Processo FAPESP: 09/53778-3 - Estudo longitudinal sobre as condições de vida e saúde dos idosos do município de São Paulo - estudo SABE
Beneficiário:Maria Lúcia Lebrão
Linha de fomento: Auxílio à Pesquisa - Temático
Processo FAPESP: 05/54947-2 - Estudo SABE - 2005: saúde, bem-estar e envelhecimento: estudo longitudinal sobre as condições de vida e saúde dos idosos no município de São Paulo
Beneficiário:Ruy Laurenti
Linha de fomento: Auxílio à Pesquisa - Temático
Processo FAPESP: 10/02779-7 - Anemia em idosos: fatores associados e impacto na síndrome de fragilidade: estudo SABE
Beneficiário:Ligiana Pires Corona
Linha de fomento: Bolsas no Brasil - Doutorado