| Full text | |
| Author(s): |
Corona, Ligiana Pires
[1]
;
Andrade, F. C. Drumond
[2]
;
de Oliveira Duarte, Y. A.
[3]
;
Lebrao, M. L.
[4]
Total Authors: 4
|
| Affiliation: | [1] Univ Estadual Campinas, Fac Sci Appl, BR-13484350 Limeira, SP - Brazil
[2] Univ Illinois, Dept Kinesiol & Community Hlth, Urbana, IL - USA
[3] Univ Sao Paulo, Sch Nursing, Dept Med Surg Nursing, Sao Paulo - Brazil
[4] Univ Sao Paulo, Dept Epidemiol, Fac Publ Hlth, Sao Paulo - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | Journal of Nutrition Health & Aging; v. 19, n. 9, p. 935-940, NOV 2015. |
| Web of Science Citations: | 11 |
| Abstract | |
to explore the relationship between anemia, hemoglobin concentration and frailty syndrome in older adults. This was a cross-sectional population-based study, with adults a parts per thousand yen60 years (n=1,256) from the third wave of the SABE Cohort Study (Health, Well-being and Aging) conducted in 2010 in So Paulo, Brazil. Frailty syndrome was evaluated according to FriedA ` s phenotype. Anemia was defined using the WHO criteria (hemoglobin concentration < 12 g/dL for women and < 13 g/dL for men). Four approaches were used to verify the associations between anemia, hemoglobin concentration and frailty status or number of frailty criteria. We used logistic regression and Poisson regression in the analyses, and they were adjusted in three hierarchical models using three blocks of variables: basic characteristics; clinical characteristics; cognitive status. Mean hemoglobin concentration was significantly lower in frail elderly (13.3g/dL, versus 14.3g/dL in non-frail; p < 0.001). Prevalence of anemia was also significantly higher in frail when compared to non-frail elderly (24.2% and 3.8%; p < 0.001). Anemia was significantly associated to low physical activity, weakness and slowness. In the fully adjusted regression models, anemia was strongly associated to frailty (OR=3.27, 95%IC=1.89,5.65; p < 0.001), and lower levels of hemoglobin were associated to higher number of frailty criteria. We found important associations between anemia, hemoglobin concentration and frailty; anemic older adults were more likely to be frail, and lower levels of hemoglobin were associated to higher number of frailty criteria showing a clear dose-response effect.. (AU) | |
| FAPESP's process: | 09/53778-3 - SABE Study 2010: Health, well-being and aging |
| Grantee: | Maria Lúcia Lebrão |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 05/54947-2 - SABE study - 2005: well-being and ageing: longitudinal study of living conditions and health of elderly in the municipality of São Paulo |
| Grantee: | Ruy Laurenti |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 10/02779-7 - Anemia in the elderly: associated factors and impact on frailty status - SABE Project |
| Grantee: | Ligiana Pires Corona |
| Support Opportunities: | Scholarships in Brazil - Doctorate |