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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Effects of anodal transcranial direct current stimulation combined with virtual reality for improving gait in children with spastic diparetic cerebral palsy: a pilot, randomized, controlled, double-blind, clinical trial

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Autor(es):
Collange Grecco, Luanda Andre [1, 2, 3] ; Carvalho Duarte, Natalia de Almeida [2] ; Mendonca, Mariana E. [4] ; Galli, Manuela [5, 6] ; Fregni, Felipe [1] ; Oliveira, Claudia Santos [2]
Número total de Autores: 6
Afiliação do(s) autor(es):
[1] Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Lab Neuromodulat, Boston, MA - USA
[2] Univ Nove de Julho, Rehabil Sci, Sao Paulo - Brazil
[3] Pediat Neurosurg Ctr CENEPE, BR-04037000 Sao Paulo, SP - Brazil
[4] Univ Sao Paulo, Inst Psychol, Neurosci & Behav, Sao Paulo - Brazil
[5] Politecn Milan, Dept Elect Informat & Bioengn, I-20133 Milan - Italy
[6] IRCCS San Raffaele Pisana, Gait Anal Lab, Rome - Italy
Número total de Afiliações: 6
Tipo de documento: Artigo Científico
Fonte: CLINICAL REHABILITATION; v. 29, n. 12, p. 1212-1223, DEC 2015.
Citações Web of Science: 28
Resumo

Objective: To compare the effects of anodal vs. sham transcranial direct current stimulation combined with virtual reality training for improving gait in children with cerebral palsy. Design: A pilot, randomized, controlled, double-blind, clinical trial. Setting: Rehabilitation clinics. Subjects: A total of 20 children with diparesis owing to cerebral palsy. Interventions: The experimental group received anodal stimulation and the control group received sham stimulation over the primary motor cortex during virtual reality training. All patients underwent the same training programme involving a virtual reality (10 sessions). Evaluations were performed before and after the intervention as well as at the one-month follow-up and involved gait analysis, the Gross Motor Function Measure, the Pediatric Evaluation Disability Inventory and the determination of motor evoked potentials. Results: The experimental group had a better performance regarding gait velocity (experimental group: 0.63 0.17 to 0.85 +/- 0.11m/s; control group: 0.73 +/- 0.15 to 0.61 +/- 0.15m/s), cadence (experimental group: 97.4 +/- 14.1 to 116.8 +/- 8.7steps/minute; control group: 92.6 +/- 10.4 to 99.7 +/- 9.7steps/minute), gross motor function (dimension D experimental group: 59.7 +/- 12.8 to 74.9 +/- 13.8; control group: 58.9 +/- 10.4 to 69.4 +/- 9.3; dimension E experimental group: 59.0 +/- 10.9 to 79.1 +/- 8.5; control group: 60.3 +/- 10.1 to 67.4 +/- 11.4) and independent mobility (experimental group: 34.3 +/- 5.9 to 43.8 +/- 75.3; control group: 34.4 +/- 8.3 to 37.7 +/- 7.7). Moreover, transcranial direct current stimulation led to a significant increase in motor evoked potential (experimental group: 1.4 +/- 0.7 to 2.6 +/- 0.4; control group: 1.3 +/- 0.6 to 1.6 +/- 0.4). Conclusion: These preliminary findings support the hypothesis that anodal transcranial direct current stimulation combined with virtual reality training could be a useful tool for improving gait in children with cerebral palsy. (AU)

Processo FAPESP: 12/24019-0 - Efeitos da estimulação transcraniana por corrente contínua associada ao treino de marcha sobre o equilíbrio estático e funcional de crianças com paralisia cerebral: ensaio clínico controlado aleatorizado, duplo cego
Beneficiário:Natália de Almeida Carvalho Duarte
Modalidade de apoio: Bolsas no Brasil - Mestrado
Processo FAPESP: 12/06519-5 - Efeito da estimulação transcraniana com corrente contínua associada ao exercício aeróbico sobre a dor de pacientes com fibromialgia
Beneficiário:Felipe Fregni
Modalidade de apoio: Auxílio à Pesquisa - Regular