Environmental Factors and Ecosystems Associated with Canine Visceral Leishmaniasis in Northeastern Brazil

Autor(es)

da Costa, Andrea Pereira ^[1] ; Costa, Francisco Borges ^[1] ; Soares, Herbert Sousa ^[1] ; Ramirez, Diego Garcia ^[1] ; Araujo, Andreina de Carvalho ^[2] ; Giuli da Silva Ferreira, Juliana Isabel ^[1] ; Tonhosolo, Renata ^[3] ; Dias, Ricardo Augusto ^[1] ; Gennari, Solange Maria ^[1] ; Marcili, Arlei ^{[3, 4, 1]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Med Vet, Dept Med Vet Prevent & Saude Anim, Sao Paulo, SP - Brazil

^[2] Univ Fed Vale Sao Francisco, Petrolina, PE - Brazil

^[3] Univ Fed ABC, Sao Paulo - Brazil

^[4] Univ Santo Amaro, Sao Paulo, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: VECTOR-BORNE AND ZOONOTIC DISEASES; v. 15, n. 12, p. 765-774, DEC 1 2015.
• Citações Web of Science: 5

Resumo

Environment influences the composition, distribution, and behavior of the vectors and mammalian hosts involved in the transmission of visceral leishmaniasis (VL), affecting the epidemiology of the disease. In Brazil, the urbanization process and canine cases of VL are indicators for local health authorities. This study aimed to investigate the occurrence of the canine visceral leishmaniasis (CVL) in MaranhAo State, Brazil. Blood samples collected from 960 dogs from six municipalities and six different ecosystems (Baixada Maranhense, Mangue, Mata dos Cocais, Amazonia, Cerrado, and Restinga) to serological tests (enzyme-linked immunosorbent assay {[}ELISA], indirect fluorescence antibody test {[}IFAT], and chromatographic immunoassay methods {[}Dual Path Platform technology, DPP (R)]) and parasitological diagnosis. From serological tests, 11.14% (107) of the dogs were positive for CVL, with 59.16% (568), 14.5% (148), and 131% (126) positives to ELISA, DPP, and IFAT tests, respectively. Only seven animals (0.73%) were positive in a parasitological test. We also performed parasite isolation and phylogenetic characterization. All isolates of dogs obtained from MaranhAo were grouped in a single branch with Leishmania infantum chagasi from Brazil. The ecosystem Amazonia presented the highest positivity rates to CVL in serological and parasitological tests. Brazilian biomes/ecosystems suffer large degradation and may favor, depending on climatic conditions, the installation of new diseases. In the case of VL, dogs are reservoirs of parasites and sentinels for human infection. (AU)

• Processo FAPESP: 10/50886-7 - Isolamento e caracterização morfológica, biológica e molecular e filogeografia multigênica de espécies causadoras de Leishmaniose visceral
• Beneficiário: Arlei Marcili
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 11/19853-8 - Estudo Epidemiológico e Aspectos Ecológicos da Leishmaniose Visceral Canina no Estado do Maranhão
• Beneficiário: Andréa Pereira da Costa
• Modalidade de apoio: Bolsas no Brasil - Doutorado