Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Structural and Ultrastructural Characteristics of Bone-Tendon Junction of the Calcaneal Tendon of Adult and Elderly Wistar Rats

Texto completo
Autor(es):
Cury, Diego Pulzatto [1, 2] ; Jose Dias, Fernando [3, 4] ; Miglino, Maria Angelica [2] ; Watanabe, Ii-sei [1, 2]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Biomed Sci, Dept Anat, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Surg, Sao Paulo - Brazil
[3] Univ Sao Paulo, Sch Med Ribeirao Preto, Dept Surg & Anat, BR-14049 Ribeirao Preto - Brazil
[4] Univ La Frontera, Sch Dent, CICO Res Ctr, Temuco - Chile
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: PLoS One; v. 11, n. 4 APR 14 2016.
Citações Web of Science: 4
Resumo

Tendons are transition tissues that transfer the contractile forces generated by the muscles to the bones, allowing movement. The region where the tendon attaches to the bone is called bone-tendon junction or enthesis and may be classified as fibrous or fibrocartilaginous. This study aims to analyze the collagen fibers and the cells present in the bone-tendon junction using light microscopy and ultrastructural techniques as scanning electron microscopy and transmission electron microscopy. Forty male Wistar rats were used in the experiment, being 20 adult rats at 4 months-old and 20 elderly rats at 20 months-old. The hind limbs of the rats were removed, dissected and prepared to light microscopy, transmission electron microscopy and scanning electron microscopy. The aging process showed changes in the collagen fibrils, with a predominance of type III fibers in the elderly group, in addition to a decrease in the amount of the fibrocartilage cells, fewer and shorter cytoplasmic processes and a decreased synthetic capacity due to degradation of the organelles involved in synthesis. (AU)

Processo FAPESP: 12/03280-1 - Características estruturais da junção osteotendínea do tríceps sural de Ratos Wistar adultos e idosos: estudo aos microscópicos de luz, microscópico eletrônico de varredura e de transmissão
Beneficiário:Diego Pulzatto Cury
Linha de fomento: Bolsas no Brasil - Mestrado