Assessing genotoxic effects in fish from a marine protected area influenced by former mining activities and other stressors

Autor(es)

Gusso-Choueri, Paloma Kachel ^{[1, 2, 3]} ; Choueri, Rodrigo Brasil ^[4] ; Santos, Gustavo Souza ^{[1, 5]} ; de Araujo, Giuliana Seraphim ^{[3, 6]} ; Feitosa Cruz, Ana Carolina ^{[3, 6]} ; Stremel, Tatiana ^[7] ; de Campos, Sandro Xavier ^[7] ; Cestari, Marta Margarete ^{[1, 5]} ; Oliveira Ribeiro, Ciro Alberto ^{[1, 2]} ; de Sousa Abessa, Denis Moledo ^[3]

Afiliação do(s) autor(es)

^[1] Fed Univ Parana UFPR, Grad Program Ecol & Conservat, CP 19031, BR-81531990 Curitiba, Parana - Brazil

^[2] Fed Univ Parana UFPR, Dept Cellular Biol, Cellular Toxicol Lab, CP19031, BR-81531990 Curitiba, Parana - Brazil

^[3] Sao Paulo State Univ, Lab Study Aquat Pollut & Ecotoxicol NEPEA, Sao Vicente Campus UNESP Campus Litoral Paulista, BR-11330900 Sao Vicente, SP - Brazil

^[4] Univ Fed Sao Paulo, Dept Marine Sci, Santos Campus UNIFESP Santos, BR-11030490 Santos, SP - Brazil

^[5] Fed Univ Parana UFPR, Dept Genet, BR-81531990 Curitiba, Parana - Brazil

^[6] Univ Sao Paulo IOUSP, Inst Oceanog, Praca Oceanog 191, BR-05508120 Sao Paulo, SP - Brazil

^[7] Univ Estadual Ponta Grossa, Res Grp Environm & Sanit Analyt Chem QAAS, Av Gen Carlos Cavalcanti 4748, BR-84030900 Ponta Grossa - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Marine Pollution Bulletin; v. 104, n. 1-2, p. 229-239, MAR 15 2016.
• Citações Web of Science: 7

Resumo

The goal of the current study was to evaluate different genotoxicity tools in order to assess a marine protected area (MPA) affected by former mining activities and urban settlements. A catfish (Cathorops spixii) was analyzed for genotoxic effects at the (i) molecular and at the (ii) chromosomal levels. Through factor analysis, genotoxicity was found to be linked to levels of metals bioaccumulated and PAH metabolites in the bile. Micronucleus and nuclear alteration were less vulnerable to the effects of confounding factors in mildly contaminated areas since they were more frequently associated with bioaccumulated metals than the DNA analysis. The different genotoxicity responses allowed for the identification of sources of pollution in the MPA. This approach was important for detecting environmental risks related to genotoxic contaminants in a mildly contaminated MPA. (C) 2016 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 09/52762-6 - Analise ecotoxicologica e biomonitoramento em bivalves do rio ribeira de iguape - avaliacao da poluicao
• Beneficiário: Denis Moledo de Souza Abessa
• Modalidade de apoio: Auxílio à Pesquisa - Regular