Oncogenetics service and the Brazilian public health system: the experience of a reference Cancer Hospital

Autor(es):Mostrar menos -

Palmero, Edenir I. ^{[1, 2, 3]} ; Galvao, Henrique C. R. ^[1] ; Fernandes, Gabriela C. ^{[1, 2]} ; de Paula, Andre E. ^{[1, 2]} ; Oliveira, Junea C. ^[1] ; Souza, Cristiano P. ^[1] ; Andrade, Carlos E. ^[1] ; Romagnolo, Luis G. C. ^[1] ; Volc, Sahlua ^[1] ; Neto, Maximiliano C. ; Sabato, Cristina ^{[1, 2]} ; Grasel, Rebeca ^[1] ; Mauad, Edmundo ^{[1, 2]} ; Reis, Rui M. ^{[4, 5, 1, 2]} ; Michelli, Rodrigo A. D. ^[1]

Afiliação do(s) autor(es)

^[1] Hosp Canc Barretos, Dept Oncogenet, Barretos, SP - Brazil

^[2] Hosp Canc Barretos, Ctr Pesquisa Oncol Mol, Ave Antenor Duarte Vilela 133, BR-14784400 Barretos, SP - Brazil

^[3] Dr Paulo Prata FACISB, Fac Ciencias Saude Barretos, Barretos, SP - Brazil

^[4] Univ Minho, Sch Hlth Sci, Life & Hlth Sci Res Inst ICVS, Braga - Portugal

^[5] ICVS 3Bs PT Govt Associate Lab, Braga - Portugal

• Tipo de documento: Artigo Científico
• Fonte: GENETICS AND MOLECULAR BIOLOGY; v. 39, n. 2, p. 168-177, APR-JUN 2016.
• Citações Web of Science: 5

Resumo

Abstract The identification of families at-risk for hereditary cancer is extremely important due to the prevention potential in those families. However, the number of Brazilian genetic services providing oncogenetic care is extremely low for the continental dimension of the country and its population. Therefore, at-risk patients do not receive appropriate assistance. This report describes the creation, structure and management of a cancer genetics service in a reference center for cancer prevention and treatment, the Barretos Cancer Hospital (BCH). The Oncogenetics Department (OD) of BCH offers, free of charge, to all patients/relatives with clinical criteria, the possibility to perform i) genetic counseling, ii) preventive examinations and iii) genetic testing with the best quality standards. The OD has a multidisciplinary team and is integrated with all specialties. The genetic counseling process consists (mostly) of two visits. In 2014, 614 individuals (371 families) were seen by the OD. To date, over 800 families were referred by the OD for genetic testing. The support provided by the Oncogenetics team is crucial to identify at-risk individuals and to develop preventive and personalized behaviors for each situation, not only to the upper-middle class population, but also to the people whose only possibility is the public health system. (AU)

• Processo FAPESP: 13/24633-2 - Caracterização molecular de famílias de alto risco para câncer de mama hereditário, negativas para mutações nos genes BRCA1/BRCA2: à procura do BRCAx
• Beneficiário: Edenir Inêz Palmero
• Modalidade de apoio: Auxílio à Pesquisa - Regular