Stabilization and detection of hydrophylloquinone as di-O-methyl derivative

Autor(es)

Sussmann, Rodrigo A. C. ; de Moraes, Marcilio M. ; Cebrian-Torrejon, Gerardo ; Porta, Exequiel O. ; Domenech-Carbo, Antonio ; Yamaguchi, Lydia F. ; Katzin, Alejandro M. ; Kato, Massuo J.

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES; v. 1033, p. 368-371, OCT 15 2016.
• Citações Web of Science: 0

Resumo

Phylloquinone is a redox active naphthoquinone involved in electron transport in plants. The function of this reduced form remains unclear due to its instability, which has precluded detection. Herein, a simple method that permits the stabilization of the reduced form of phylloquinone by di-O-methylation and HPLC detection is described. (C) 2016 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 09/51850-9 - Diversidade molecular em Angiospermas basais
• Beneficiário: Massuo Jorge Kato
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOEN - Temático
• Processo FAPESP: 14/23417-7 - Biossíntese de isoprenóides em Plasmodium falciparum: avaliação de possíveis alvos para a obtenção de novas drogas anti-maláricas
• Beneficiário: Alejandro Miguel Katzin
• Modalidade de apoio: Auxílio à Pesquisa - Regular