Stabilization and detection of hydrophylloquinone as di-O-methyl derivative

Sussmann, Rodrigo A. C.; de Moraes, Marcilio M.; Cebrian-Torrejon, Gerardo; Porta, Exequiel O.; Domenech-Carbo, Antonio; Yamaguchi, Lydia F.; Katzin, Alejandro M.; Kato, Massuo J.

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Stabilization and detection of hydrophylloquinone as di-O-methyl derivative

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Author(s):	Sussmann, Rodrigo A. C. ; de Moraes, Marcilio M. ; Cebrian-Torrejon, Gerardo ; Porta, Exequiel O. ; Domenech-Carbo, Antonio ; Yamaguchi, Lydia F. ; Katzin, Alejandro M. ; Kato, Massuo J. Total Authors: 8
Document type:	Journal article
Source:	JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES; v. 1033, p. 368-371, OCT 15 2016.
Web of Science Citations:	0
Abstract
Phylloquinone is a redox active naphthoquinone involved in electron transport in plants. The function of this reduced form remains unclear due to its instability, which has precluded detection. Herein, a simple method that permits the stabilization of the reduced form of phylloquinone by di-O-methylation and HPLC detection is described. (C) 2016 Elsevier B.V. All rights reserved. (AU)

FAPESP's process:	14/23417-7 - Biosynthesis of isoprenoids in Plasmodium falciparum: evaluation of possible targets for to obtain new anti-malarial drugs
Grantee:	Alejandro Miguel Katzin
Support Opportunities:	Regular Research Grants

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