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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Association between Polyphenol Intake and Hypertension in Adults and Older Adults: A Population-Based Study in Brazil

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Autor(es):
Miranda, Andreia Machado ; Steluti, Josiane ; Fisberg, Regina Mara ; Marchioni, Dirce Maria
Número total de Autores: 4
Tipo de documento: Artigo Científico
Fonte: PLoS One; v. 11, n. 10 OCT 28 2016.
Citações Web of Science: 24
Resumo

Background/Objective Hypertension is an important risk factor for cardiovascular disease, and diet has been identified as a modifiable factor for preventing and controlling hypertension. Besides, epidemiological studies have suggested an inverse association between polyphenol intake and cardiovascular diseases. The aim of this study was to evaluate the association between the intake of polyphenols and hypertension in a general population of Sao Paulo. Methods Data came from the `Health Survey of Sao Paulo (ISA-Capital)' among 550 adults and older adults in Sao Paulo, Brazil. Diet was assessed by two 24-hour dietary recalls (24HR). Usual intakes were calculated using the Multiple Source Method. Polyphenol intake was calculated by matching food consumption data from the 24HR with the Phenol-Explorer database. The associations between the hypertension and tertiles of the total and classes of polyphenols intake were tested by multivariate logistic regression analysis. Results After multivariate adjustment for potential confounding factors the findings showed an inverse and linearly association between the hypertension and highest tertiles of tyrosols (OR = 0.33; 95% CI 0.18, 0.64), alkylphenols (OR = 0.45; 95% CI 0.23, 0.87), lignans (OR = 0.49; 95% CI 0.25, 0.98), as well as stilbenes (OR = 0.60; 95% CI 0.36, 0.98), and other polyphenols (OR = 0.33; 95% CI 0.14, 0.74). However, total polyphenol intake, and phenolic acids were significantly associated only in the middle tertile with hypertension and flavonoids were not significant associated. Conclusion There is an inverse and linearly association between the highest tertile of some classes of polyphenols, such as, tyrosols, alkylphenols, lignans, stilbenes, other polyphenols and hypertension. (AU)

Processo FAPESP: 09/15831-0 - Fatores dietéticos, homocisteína, polimorfismos do gene MTHFR e risco cardiovascular em adultos e idosos: estudo de base populacional - ISA - capital
Beneficiário:Regina Mara Fisberg
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 14/04540-2 - Estudo epidemiológico do consumo do café, sua contribuição na ingestão de polifenóis e seus potenciais efeitos nos fatores de risco cardiovascular, considerando variações genéticas individuais
Beneficiário:Andreia Alexandra Machado Miranda
Linha de fomento: Bolsas no Brasil - Doutorado