Hypoxia during embryonic development increases energy metabolism in normoxic juvenile chicks

Autor(es)

do Amaral-Silva, Lara ; Scarpellini, Carolina da S. ; Toro-Velasquez, Paula Andrea ; Fernandes, Marcia H. M. R. ; Gargaglioni, Luciane H. ; Bicego, Kenia C.

• Tipo de documento: Artigo Científico
• Fonte: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY; v. 207, p. 93-99, MAY 2017.
• Citações Web of Science: 2

Resumo

Environmental changes during perinatal development can affect the postnatal life. In this sense, chicken embryos that experience low levels of O-2 over a specific phase of incubation can have their tissue growth reduced and the ventilatory response to hypoxia blunted, at least until hatching. Additionally, exposure to low level of 02 after birth reduces the thermogenesis as well. In the present study, we tested the hypothesis that hypoxia over the third week of incubation affects the thermoregulation of juvenile chicks at an age when thermogenesis is already expected to be well-developed. To this end, we measured body temperature (Tb) and oxygen consumption (V0(2)) under acute hypoxia or different ambient temperatures (Ta) of 1 and 10 day-old chicks that have been exposed to 21%O-2 for entire incubation (Nx) or to 15% O-2 in the last week of incubation (Hx). We also assessed the thermal preference under normoxia or acute hypoxia of the older chicks from both incubation groups in a thermocline. Hypoxia over incubation reduced growth but did not affect the cold-induced thermogenesis in hatchlings. Regarding the juvenile Hx, present data indicate a catch up growth with higher resting V0(2), a thermal preference for warmer Tas and a possible higher thermal conductance. In conclusion, our results show that hypoxia over the third week of incubation can affect the thermoregulation at least until 10 days after hatch in chickens. (C) 2017 Elsevier Inc All rights reserved. (AU)

• Processo FAPESP: 11/19131-2 - Participação dos canais TRPV4 hipotalâmicos na ativação/inibição dos termoefetores autonômicos durante a febre e o choque endotoxêmico
• Beneficiário: Carolina da Silveira Scarpellini
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 10/20285-1 - Exposição à hipóxia durante a incubação e sua influência na preferência térmica e na curva metabólica de pintos de corte nas primeiras semanas pós-eclosão
• Beneficiário: Kênia Cardoso Bícego
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 14/01861-2 - Efeito da hipóxia na fase final da incubação sobre as estruturas pulmonares pós eclosão em pintainhos de frangos de corte
• Beneficiário: Lara do Amaral Silva
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 11/07509-0 - Exposição à hipóxia durante a incubação e sua influência na preferência térmica e na curva metabólica de pintos de corte nas primeiras semanas pós-eclosão
• Beneficiário: Paula Andrea Toro Velásquez
• Modalidade de apoio: Bolsas no Brasil - Doutorado