Antibodies to Shiga toxins in Brazilian cattle

Autor(es)

Yamamoto, Bruno B. ; Luz, Daniela ; Abreu, Patricia A. E. ; Gotti, Tatiana B. ; Vasconcellos, Silvio A. ; Piazza, Roxane M. P. ; Horton, Denise S. P. Q.

• Tipo de documento: Artigo Científico
• Fonte: Toxicon; v. 133, p. 58-62, JUL 2017.
• Citações Web of Science: 0

Resumo

Cattle are considered a reservoir of Shiga toxin-producing Escherichia coli (STEC). There is no information about the presence of antibodies against Shiga toxins in Brazilian bovine serum. Using ELISA, all sera tested showed antibodies against the two main STEC virulence factors; Stx1 and Stx2. Neutralizing antibodies against Stx1 and/or Stx2 were detected in all but one serum. In conclusion, our results indicated that these animals had been exposed to STEC producing both toxins. (C) 2017 Elsevier Ltd. All rights reserved. (AU)

• Processo FAPESP: 11/12928-2 - Novo desafio para o diagnóstico de Escherichia coli diarreiogênica: obtenção de anticorpos recombinantes contra diferentes fatores de virulência
• Beneficiário: Roxane Maria Fontes Piazza
• Modalidade de apoio: Auxílio à Pesquisa - Regular