Antibodies to Shiga toxins in Brazilian cattle

Yamamoto, Bruno B.; Luz, Daniela; Abreu, Patricia A. E.; Gotti, Tatiana B.; Vasconcellos, Silvio A.; Piazza, Roxane M. P.; Horton, Denise S. P. Q.

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Antibodies to Shiga toxins in Brazilian cattle

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Author(s):	Yamamoto, Bruno B. ; Luz, Daniela ; Abreu, Patricia A. E. ; Gotti, Tatiana B. ; Vasconcellos, Silvio A. ; Piazza, Roxane M. P. ; Horton, Denise S. P. Q. Total Authors: 7
Document type:	Journal article
Source:	Toxicon; v. 133, p. 58-62, JUL 2017.
Web of Science Citations:	0
Abstract
Cattle are considered a reservoir of Shiga toxin-producing Escherichia coli (STEC). There is no information about the presence of antibodies against Shiga toxins in Brazilian bovine serum. Using ELISA, all sera tested showed antibodies against the two main STEC virulence factors; Stx1 and Stx2. Neutralizing antibodies against Stx1 and/or Stx2 were detected in all but one serum. In conclusion, our results indicated that these animals had been exposed to STEC producing both toxins. (C) 2017 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process:	11/12928-2 - New challenge for the diagnosis of diarrheagenic Escherichia coli: recombinant antibody obtention against different virulence factors
Grantee:	Roxane Maria Fontes Piazza
Support type:	Regular Research Grants

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