Homeostasis Model Assessment-Adiponectin: the role of different types of physical exercise in obese adolescents

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da Silveira Campos, Raquel M. ; Landi Masquio, Deborah C. ; Corgosinho, Flvia Campos ; Sanches, Priscila de Lima ; de Piano, Aline ; Carnier, June ; da Silva, Patricia Leao ; Grotti Clemente, Ana P. ; de Castro Ferreira Vicente, Sofia E. ; Oyama, Lila M. ; da Penha Oller do Nascimento, Claudia M. ; Tock, Lian ; Tufik, Sergio ; de Mello, Marco T. ; Damaso, Ana R.

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS; v. 57, n. 6, p. 831-838, JUN 2017.
• Citações Web of Science: 2

Resumo

BACKGROUND: Homeostasis Model Assessment-Adiponectin (HOMA-AD) is suggesting a new biomarker of insulin resistance in obese population. In this way, the purpose of this study was to investigate the effects of different kinds of exercise in the sensitive index predictor of insulin resistance. METHODS: A total of 148 obese adolescents were enrolled in the program. They aged 15-19 y, with Body Mass Index (BMI)>= P95(th) and were submitted to 1 year of interdisciplinary weight loss therapy, randomized in two groups, aerobic training (AT) (N.=51) and aerobic plus resistance training (N.=97). Blood samples were collected to analyze adiponectin, glucose and insulin concentrations. The insulin resistance was measured by HOMA-AD and Homeostasis Model Assessment Insulin Resistance Index (HOMA-IR). RESULTS: Both kinds of exercise training promoted a decrease in body mass, body mass index, fat mass, visceral and subcutaneous fat. However, only aerobic plus resistance training was effective to reduce HOMA-AD, insulin and glucose concentration; and increase insulin sensibility and adiponectin concentration. CONCLUSIONS: The aerobic plus resistance training was more effective than AT alone to improve the HOMA-AD, suggesting clinical application on obesity, diabetes, atherosclerosis and metabolic syndrome control in the pediatric population. (AU)

• Processo FAPESP: 11/50414-0 - Influência da hiperleptinemia nas respostas inflamatórias e aterogênicas em adolescentes obesos
• Beneficiário: Ana Raimunda Dâmaso
• Linha de fomento: Auxílio à Pesquisa - Regular
• Processo FAPESP: 15/14309-9 - Efeitos do exercício físico associado à fototerapia sobre os marcadores da adipogênese e transdiferenciação do tecido adiposo em mulheres adultas com obesidade
• Beneficiário: Raquel Munhoz da Silveira Campos
• Linha de fomento: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 11/50356-0 - Análise de complemento protéico plasmático e de fatores de risco metabólicos em adolescentes obesos em tratamento no Centro de Recuperação e Educação Nutricional (CREN)
• Beneficiário: Ana Raimunda Dâmaso
• Linha de fomento: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/04136-4 - Análise da regulação neuroendócrina do balanço energético e fatores inflamatórios em obesos adultos submetidos à cirurgia bariátrica
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• Linha de fomento: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/08522-6 - Novas perspectivas terapêuticas na obesidade
• Beneficiário: Ana Raimunda Dâmaso
• Linha de fomento: Auxílio à Pesquisa - Regular