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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Homeostasis Model Assessment-Adiponectin: the role of different types of physical exercise in obese adolescents

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Author(s):
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da Silveira Campos, Raquel M. ; Landi Masquio, Deborah C. ; Corgosinho, Flvia Campos ; Sanches, Priscila de Lima ; de Piano, Aline ; Carnier, June ; da Silva, Patricia Leao ; Grotti Clemente, Ana P. ; de Castro Ferreira Vicente, Sofia E. ; Oyama, Lila M. ; da Penha Oller do Nascimento, Claudia M. ; Tock, Lian ; Tufik, Sergio ; de Mello, Marco T. ; Damaso, Ana R.
Total Authors: 15
Document type: Journal article
Source: JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS; v. 57, n. 6, p. 831-838, JUN 2017.
Web of Science Citations: 1
Abstract

BACKGROUND: Homeostasis Model Assessment-Adiponectin (HOMA-AD) is suggesting a new biomarker of insulin resistance in obese population. In this way, the purpose of this study was to investigate the effects of different kinds of exercise in the sensitive index predictor of insulin resistance. METHODS: A total of 148 obese adolescents were enrolled in the program. They aged 15-19 y, with Body Mass Index (BMI)>= P95(th) and were submitted to 1 year of interdisciplinary weight loss therapy, randomized in two groups, aerobic training (AT) (N.=51) and aerobic plus resistance training (N.=97). Blood samples were collected to analyze adiponectin, glucose and insulin concentrations. The insulin resistance was measured by HOMA-AD and Homeostasis Model Assessment Insulin Resistance Index (HOMA-IR). RESULTS: Both kinds of exercise training promoted a decrease in body mass, body mass index, fat mass, visceral and subcutaneous fat. However, only aerobic plus resistance training was effective to reduce HOMA-AD, insulin and glucose concentration; and increase insulin sensibility and adiponectin concentration. CONCLUSIONS: The aerobic plus resistance training was more effective than AT alone to improve the HOMA-AD, suggesting clinical application on obesity, diabetes, atherosclerosis and metabolic syndrome control in the pediatric population. (AU)

FAPESP's process: 11/50414-0 - Influence of hyperleptinemia on inflammatory and atherogenic responses in obese adolescents
Grantee:Ana Raimunda Dâmaso
Support type: Regular Research Grants
FAPESP's process: 15/14309-9 - Effects of physical exercise associate with phototherapy on adipogenesis biomarkers and transdifferentiation of adipose tissue in adult obese women
Grantee:Raquel Munhoz da Silveira Campos
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 13/04136-4 - Analysis of neuroendocrine regulation of balance energy and inflammatory factors in obese adults submitted to bariatric surgery
Grantee:Ana Raimunda Dâmaso
Support type: Regular Research Grants
FAPESP's process: 13/08522-6 - New therapeutic perspectives in obesity
Grantee:Ana Raimunda Dâmaso
Support type: Regular Research Grants