Influence of hyperleptinemia on inflammatory and atherogenic responses in obese adolescents

• Grant number: 11/50414-0
• Support type: Regular Research Grants
• Duration: October 01, 2011 - September 30, 2013
• Field of knowledge: Health Sciences - Nutrition
• Principal Investigator: Ana Raimunda Dâmaso
• Grantee: Ana Raimunda Dâmaso
• Home Institution: Instituto de Saúde e Sociedade (ISS). Universidade Federal de São Paulo (UNIFESP). Campus Baixada Santista. Santos , SP, Brazil

Abstract

Currently, obesity is a major public health problem. An estimated 300 million adults and nearly 40 million of children and adolescents worldwide are clinically obese. This increase in obesity in early childhood is associated with the development of many cardiovascular diseases, which highlights the atherosclerosis. Aim: To verify the role of hyperleptinemia on inflammatory and atherogenic response in obese adolescents. (AU)

Scientific publications

(18)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; LANDI MASQUIO, DEBORAH CRISTINA; CORGOSINHO, FLAVIA CAMPOS; CARANTI, DANIELLE ARISA; GANEN, ALINE DE PIANO; TOCK, LIAN; OYAMA, LILA MISSAE; DAMASO, ANA RAIMUNDA. Effects of magnitude of visceral adipose tissue reduction: Impact on insulin resistance, hyperleptinemia and cardiometabolic risk in adolescents with obesity after long-term weight-loss therapy. Diabetes & Vascular Disease Research, v. 16, n. 2, SI, p. 196-206, MAR 2019. Web of Science Citations: 1.

CORGOSINHO, FLAVIA CAMPOS; ALMEIDA, SANDRO SOARES; TOCK, LIAN; PESQUERO, JOAO BOSCO; ARAUJO, RONALDO CARVALHO; GROTTI CLEMENTE, ANA PAULA; NETTO, BARBARA DAL'MOLIN; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; LANDI MASQUIO, DEBORAH CRISTINA; DE CARVALHO FERREIRA, JOANA PEREIRA; SANCHES, PRISCILA DE LIMA; GANEN, ALINE DE PIANO; ROGERO, MARCELO MACEDO; OYAMA, LILA MISSAE; TUFIK, SERGIO; DE MELLO, MARCO TULIO; DAMASO, ANA RAIMUNDA. LEPR polymorphism may affect energy balance during weight loss among Brazilians obese adolescents. Neuropeptides, v. 66, p. 18-24, DEC 2017. Web of Science Citations: 3.

DA SILVEIRA CAMPOS, RAQUEL M.; LANDI MASQUIO, DEBORAH C.; CORGOSINHO, FLVIA CAMPOS; SANCHES, PRISCILA DE LIMA; DE PIANO, ALINE; CARNIER, JUNE; DA SILVA, PATRICIA LEAO; GROTTI CLEMENTE, ANA P.; DE CASTRO FERREIRA VICENTE, SOFIA E.; OYAMA, LILA M.; DA PENHA OLLER DO NASCIMENTO, CLAUDIA M.; TOCK, LIAN; TUFIK, SERGIO; DE MELLO, MARCO T.; DAMASO, ANA R. Homeostasis Model Assessment-Adiponectin: the role of different types of physical exercise in obese adolescents. JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS, v. 57, n. 6, p. 831-838, JUN 2017. Web of Science Citations: 1.

ALMEIDA, SANDRO S.; CORGOSINHO, FLAVIA C.; AMORIM, CARLOS E. N.; GREGNANI, MARCOS F.; CAMPOS, RAQUEL M. S.; MASQUIO, DEBORAH C. L.; SANCHES, PRISCILA L.; GANEN, ALINE P.; PESQUERO, JOAO B.; DAMASO, ANA R.; MELLO, MARCO T.; TUFIK, SERGIO; ARAUJO, RONALDO C. Different metabolic responses induced by long-term interdisciplinary therapy in obese adolescents related to ACE I/D polymorphism. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, v. 18, n. 2 APR-JUN 2017. Web of Science Citations: 0.

LANDI MASQUIO, DEBORAH CRISTINA; DE PIANO-GANEN, ALINE; OYAMA, LILA MISSAE; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; SANTAMARINAA, ALINE BOVETO; DE MORAIS HONORATO DE SOUZA, GABRIEL INACIO; GOMES, ALINE DAL'OLIO; MOREIRA, RENATA GUIMARAES; CORGOSINHO, FLAVIA CAMPOS; OLLER DO NASCIMENTO, CLAUDIA MARIA; TOCK, LIAN; TUFIK, SERGIO; DE MELLO, MARCO TULIO; DAMASO, ANA R. The role of free fatty acids in the inflammatory and cardiometabolic profile in adolescents with metabolic syndrome engaged in interdisciplinary therapy. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, v. 33, p. 136-144, JUL 2016. Web of Science Citations: 7.

CORGOSINHO, FLAVIA CAMPOS; ACKEL-D'ELIA, CAROLINA; TUFIK, SERGIO; DAMASO, ANA RAIMUNDA; DE PIANO, ALINE; SANCHES, PRISCILA DE LIMA; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; SILVA, PATRICIA LEAO; CARNIER, JUNE; TOCK, LIAN; ANDERSEN, MONICA LEVY; MOREIRA, GUSTAVO ANTONIO; PRADELLA-HALLINAN, MARCIA; OYAMA, LILA MISSAE; DE MELLO, MARCO TULIO. Beneficial Effects of a Multifaceted 1-Year Lifestyle Intervention on Metabolic Abnormalities in Obese Adolescents With and Without Sleep-Disordered Breathing. METABOLIC SYNDROME AND RELATED DISORDERS, v. 13, n. 3, p. 110-118, APR 1 2015. Web of Science Citations: 5.

LANDI MASQUIO, DEBORAH CRISTINA; GANEN, ALINE DE PIANO; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; SANCHES, PRISCILA DE LIMA; CORGOSINHO, FLAVIA CAMPOS; CARANTI, DANIELLE; TOCK, LIAN; DE MELLO, MARCO TULIO; TUFIK, SERGIO; DAMASO, ANA R. Cut-off values of waist circumference to predict metabolic syndrome in obese adolescents. NUTRICION HOSPITALARIA, v. 31, n. 4, p. 1540-1550, APR 2015. Web of Science Citations: 7.

DE CARVALHO-FERREIRA, JOANA PEREIRA; LANDI MASQUIO, DEBORAH CRISTINA; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; NETTO, BARBARA DAL MOLIN; CORGOSINHO, FLAVIA CAMPOS; SANCHES, PRISCILA L.; TOCK, LIAN; TUFIK, SERGIO; DE MELLO, MARCO TULIO; FINLAYSON, GRAHAM; DAMASO, ANA R. Is there a role for leptin in the reduction of depression symptoms during weight loss therapy in obese adolescent girls and boys?. Peptides, v. 65, p. 20-28, MAR 2015. Web of Science Citations: 5.

SANCHES, PRISCILA L.; DE PIANO, ALINE; CAMPOS, RAQUEL M. S.; CARNIER, JUNE; DE MELLO, MARCO T.; ELIAS, NATALIA; FONSECA, FRANCISCO A. H.; MASQUIO, DEBORAH C. L.; DA SILVA, PATRICIA L.; CORGOSINHO, FLAVIA C.; TOCK, LIAN; OYAMA, LILA M.; TUFIK, SERGIO; DAMASO, ANA R. Association of nonalcoholic fatty Liver disease with cardiovascular risk factors in obese adolescents: The role of interdisciplinary therapy. JOURNAL OF CLINICAL LIPIDOLOGY, v. 8, n. 3, p. 265-272, JUN 2014. Web of Science Citations: 19.

MASQUIO, D. C. L.; DE PIANO, A.; CAMPOS, R. M. S.; SANCHES, P. L.; CORGOSINHO, F. C.; CARNIER, J.; OYAMA, L. M.; DO NASCIMENTO, C. M. P. O.; DE MELLO, M. T.; TUFIK, S.; DAMASO, A. R. Saturated Fatty Acid Intake Can Influence Increase in Plasminogen Activator Inhibitor-1 in Obese Adolescents. Hormone and Metabolic Research, v. 46, n. 4, p. 245-251, APR 2014. Web of Science Citations: 12.

CAMPOS, RAQUEL M. S.; DE MELLO, MARCO T.; TOCK, LIAN; SILVA, PATRICIA L.; MASQUIO, DEBORAH C. L.; DE PIANO, ALINE; SANCHES, PRISCILA L.; CARNIER, JUNE; CORGOSINHO, FLAVIA C.; FOSCHINI, DENIS; TUFIK, SERGIO; DAMASO, ANA R. Aerobic Plus Resistance Training Improves Bone Metabolism and Inflammation in Adolescents who Are Obese. JOURNAL OF STRENGTH AND CONDITIONING RESEARCH, v. 28, n. 3, p. 758-766, MAR 2014. Web of Science Citations: 19.

ACKEL-D'ELIA, C.; CARNIER, J.; BUENO, JR., C. R.; CAMPOS, R. M. S.; SANCHES, P. L.; CLEMENTE, A. P. G.; TUFIK, S.; DE MELLO, M. T.; DAMASO, A. R. Effects of Different Physical Exercises on Leptin Concentration in Obese Adolescents. INTERNATIONAL JOURNAL OF SPORTS MEDICINE, v. 35, n. 2, p. 164-171, FEB 2014. Web of Science Citations: 15.

NETTO, BARBARA DAL MOLIN; LANDI MASQUIO, DEBORAH CRISTINA; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; SANCHES, PRISCILA DE LIMA; CORGOSINHO, FLAVIA CAMPOS; TOCK, LIAN; OYAMA, LILA MISSAE; DE MELLO, MARCO TULIO; TUFIK, SERGIO; DAMASO, ANA RAIMUNDA. The high glycemic index diet was an independent predictor to explain changes in agouti-related protein in obese adolescents. NUTRICION HOSPITALARIA, v. 29, n. 2, p. 305-314, FEB 2014. Web of Science Citations: 0.

SANCHES, PRISCILA L.; DE MELLO, MARCO T.; ELIAS, NATALIA; FONSECA, FRANCISCO A. H.; CAMPOS, RAQUEL M. S.; CARNIER, JUNE; DE PIANO, ALINE; MASQUIO, DEBORAH C. L.; SILVA, PATRICIA L.; OYAMA, LILA M.; CORGOSINHO, FLAVIA C.; NASCIMENTO, CLAUDIA M. O.; TOCK, LIAN; D'ELIA, CAROLINA ACKEL; TUFIK, SERGIO; DAMASO, ANA R. Hyperleptinemia: Implications on the Inflammatory State and Vascular Protection in Obese Adolescents Submitted to an Interdisciplinary Therapy. Inflammation, v. 37, n. 1, p. 35-43, FEB 2014. Web of Science Citations: 14.

DAMASO, ANA RAIMUNDA; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; CARANTI, DANIELLE ARISA; DE PIANO, ALINE; FISBERG, MAURO; FOSCHINI, DENIS; SANCHES, PRISCILA DE LIMA; TOCK, LIAN; LEDERMAN, HENRIQUE MANOEL; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Aerobic plus resistance training was more effective in improving the visceral adiposity, metabolic profile and inflammatory markers than aerobic training in obese adolescents. JOURNAL OF SPORTS SCIENCES, v. 32, n. 15, p. 1435-1445, 2014. Web of Science Citations: 29.

DAMASO, ANA RAIMUNDA; DE PIANO, ALINE; DA SILVEIRA CAMPOS, RAQUEL MUNHOZ; CORGOSINHO, FLAVIA CAMPOS; SIEGFRIED, WOLFGANG; CARANTI, DANIELLE ARISA; LANDI MASQUIO, DEBORAH CRISTINA; CARNIER, JUNE; SANCHES, PRISCILA DE LIMA; DA SILVA, PATRICIA LEAO; OLLER NASCIMENTO, CLAUDIA MARIA; OYAMA, LILA MISSAE; AGUILERA DANTAS, ALEXANDRE DAMASO; DE MELLO, MARCO TULIO; TUFIK, SERGIO; TOCK, LIAN. Multidisciplinary Approach to the Treatment of Obese Adolescents: Effects on Cardiovascular Risk Factors, Inflammatory Profile, and Neuroendocrine Regulation of Energy Balance. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, 2013. Web of Science Citations: 22.

SANCHES, PRISCILA DE LIMA; DE MELLO, MARCO TULIO; HELFESTEIN FONSECA, FRANCISCO ANTONIO; ELIAS, NATALIA; DE PIANO, ALINE; CARNIER, JUNE; TOCK, LIAN; OYAMA, LILA MISSAE; TUFIK, SERGIO; DAMASO, ANA. Insulin Resistance Can Impair Reduction on Carotid Intima-Media Thickness in Obese Adolescents. Arquivos Brasileiros de Cardiologia, v. 99, n. 4, p. 892-897, OCT 2012. Web of Science Citations: 6.

LIRA, FABIO S.; ROSA, JOSE C.; PIMENTEL, GUSTAVO D.; SANTOS, RONALDO V.; CARNIER, JUNE; SANCHES, PRISCILA L.; DE PIANO, ALINE; DE SOUZA, CLAUDIO T.; TOCK, LIAN; TUFIK, SERGIO; DE MELLO, MARCO T.; SEELAENDER, MARILIA; OLLER DO NASCIMENTO, CLAUDIA M.; OYAMA, LILA M.; DAMASO, ANA R. Long-term interdisciplinary therapy reduces endotoxin level and insulin resistance in obese adolescents. NUTRITION JOURNAL, v. 11, SEP 18 2012. Web of Science Citations: 16.