Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Exposure to crack cocaine causes adverse effects on marine mussels Perna perna

Texto completo
Autor(es):
Mostrar menos -
Maranho, L. A. [1] ; Fontes, M. K. [1] ; Kamimura, A. S. S. [2] ; Nobre, C. R. [2] ; Moreno, B. B. [1] ; Pusceddu, F. H. [2] ; Cortez, F. S. [2] ; Lebre, D. T. [3] ; Marques, J. R. [3] ; Abessa, D. M. S. [4] ; Ribeiro, D. A. [5] ; Pereira, C. D. S. [1]
Número total de Autores: 12
Afiliação do(s) autor(es):
[1] Univ Fed Sao Paulo, Dept Ciencias Mar, Rua Dr Carvalho Mendonga 144, BR-11070102 Santos - Brazil
[2] Univ Santa Cecilia, Lab Ecotoxicol, Rua Oswaldo Cruz 266, BR-11045907 Santos - Brazil
[3] CIETEC IPEN, CEMSA Ctr Espectrometria Massas Aplicada, Ave Prof Lineu Prestes 2242, Salas 112 & 113, BR-05508000 Sao Paulo - Brazil
[4] Univ Estadual Paulista, Campus Litoral Paulista, Inst Biociencias, Infante Dom Henrique S-N, BR-11330900 Sao Vicente - Brazil
[5] Univ Fed Sao Paulo, Dept Biociencias, Av Ana Costa 95, BR-11060001 Santos - Brazil
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: Marine Pollution Bulletin; v. 123, n. 1-2, p. 410-414, OCT 15 2017.
Citações Web of Science: 7
Resumo

Our study aimed to evaluate crack cocaine effects in different life stages of the marine mussel Perna perm. For this purpose, fertilization rate, embryo-larval development, lysosomal membrane stability and DNA strand breaks were assessed. Effect concentrations in gametes and in larval development were found after 1 h (IC50 = 23.53 mg.L-1) and 48 h (IC50 = 16.31 mg.L-1),respectively. The highest tested concentration showing no acute toxicity (NOEC) was 10 mg.L-1, while the lowest observed effect concentration (LOEC) was 20 mg.L-1. NOEC concerning embryo-larval development was 0.625 mg.L-1, while the LOEC was 1.25 mg.L-1. Cyto-genotoxic effects were evidenced in mussels exposed to crack cocaine concentrations ranging from 5 to 500 mu g.L-1. Our results report the first data on effects of an illicit drug to marine organisms and should encourage further ecotoxicological studies of these contaminants of emerging concern in coastal ecosystems. (AU)

Processo FAPESP: 15/17329-0 - Estudo ecotoxicológico e avaliação do risco ambiental de drogas ilícitas em ecossistemas marinhos
Beneficiário:Camilo Dias Seabra Pereira
Linha de fomento: Auxílio à Pesquisa - Regular