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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Assessing Risk of Bias in Randomized Controlled Trials for Autism Spectrum Disorder

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Autor(es):
Martins Okuda, Paola Matiko [1] ; Klaiman, Cheryl [2, 3] ; Bradshaw, Jessica [2, 3] ; Reid, Morganne [3] ; Cogo-Moreira, Hugo [1]
Número total de Autores: 5
Afiliação do(s) autor(es):
[1] Univ Fed Sao Paulo, Dept Psychiat, Sao Paulo - Brazil
[2] Emory Univ, Sch Med, Atlanta, GA - USA
[3] Childrens Healthcare Atlanta, Marcus Autism Ctr, Atlanta, GA - USA
Número total de Afiliações: 3
Tipo de documento: Artigo Científico
Fonte: FRONTIERS IN PSYCHIATRY; v. 8, NOV 29 2017.
Citações Web of Science: 4
Resumo

Aim: To determine construct validity and reliability indicators of the Cochrane risk of bias (RoB) tool in the context of randomized clinical trials (RCTs) for autism spectrum disorder (ASD). Methods: Confirmatory factor analysis was used to evaluate a unidimensional model consisting of 9 RoB categorical indicators evaluated across 94 RCTs addressing interventions for ASD. Results: Only five of the nine original RoB items returned good fit indices and so were retained in the analysis. Only one of this five had very high factor loadings. The remaining four indicators had more measurement error than common variance with the RoB latent factor. Together, the five indicators showed poor reliability (omega = 0.687; 95% CI: 0.613-0.761). Conclusion: Although the Cochrane model of RoB for ASD exhibited good fit indices, the majorities of the items have more residual variance than common variance and, therefore, did not adequately capture the RoB in ASD intervention trials. (AU)

Processo FAPESP: 15/04619-0 - Análise psicométrica de dois testes da avaliação motora Movement Assessment Batery for Children, second edition - MABC-2 e Bruininks-Oseretsky Test of Motor Proficiency: aplicação de análise fatorial, de classes latentes e modelos híbridos (mistos)
Beneficiário:Paola Matiko Martins Okuda
Linha de fomento: Bolsas no Brasil - Doutorado