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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Cardiac Remodeling Patterns in Severe Obesity According to Arterial Hypertension Grade

Texto completo
Autor(es):
de Cleva, Roberto [1, 2] ; Araujo, Victor Arrais [1] ; Ornelas Buchalla, Carla Cristina [1] ; Costa, Fabio de Oliveira [1] ; Cardoso, Acacio Fernandes [1] ; Pajecki, Denis [1] ; Santo, Marco Aurelio [1]
Número total de Autores: 7
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Hosp Clin, Dept Gastroenterol, Sch Med, AVe Dr Arnaldo 455, BR-01246000 Sao Paulo, SP - Brazil
[2] Rua Cel Artur Godoi 125, Apto 152, BR-04018050 Sao Paulo, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: OBESITY SURGERY; v. 28, n. 4, p. 1047-1054, APR 2018.
Citações Web of Science: 2
Resumo

The purpose of this study is to correlate the left ventricular hypertrophy (LVH) patterns according to severe obesity and arterial hypertension (AHT) grades. A cross-sectional prospective study was conducted in 379 patients with severe obesity. Obesity was classified according to the BMI in the following: morbidly obese (MO; 40 < BMI < 50 kg/m(2)) and super obese (SO; BMI > 50 kg/m(2)). The AHT was classified into classes 1 and 2 according to American Heart Association. The presence of LVH and the pattern of cardiac remodeling were determined by transthoracic echocardiography. LVH was present in 58.6% of patients. Obesity and AHT had additive effects in LVH prevalence. LVH was found in 32.9 and 46.7% of MO with AHT grades 1 and 2, respectively. LVH was diagnosed in 39.1% in SO with AHT grade 1 and in 50% of AHT grade 2. Patients with AHT presented a significantly higher risk of developing LVH (OR 1.97; p = 0.003). Hypertension grade was also a determinant variable in the development of LVH. Patients with AHT 2 had 4.31-fold greater risk (p < 0.001) when compared to normotensive patients. BMI was only considered an independent risk factor for LVH in patients with BMI greater than 47.17 kg/m(2) (OR 1.62; p = 0.023). AHT is a stronger predictive factor of LVH than obesity grade. (AU)

Processo FAPESP: 15/12265-4 - Padrões de remodelamento cardíaco na obesidade mórbida de acordo com o grau da obesidade e a gravidade da hipertensão arterial sistêmica
Beneficiário:Victor Arrais Araujo
Modalidade de apoio: Bolsas no Brasil - Iniciação Científica