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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Cardiac Remodeling Patterns in Severe Obesity According to Arterial Hypertension Grade

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Author(s):
de Cleva, Roberto [1, 2] ; Araujo, Victor Arrais [1] ; Ornelas Buchalla, Carla Cristina [1] ; Costa, Fabio de Oliveira [1] ; Cardoso, Acacio Fernandes [1] ; Pajecki, Denis [1] ; Santo, Marco Aurelio [1]
Total Authors: 7
Affiliation:
[1] Univ Sao Paulo, Hosp Clin, Dept Gastroenterol, Sch Med, AVe Dr Arnaldo 455, BR-01246000 Sao Paulo, SP - Brazil
[2] Rua Cel Artur Godoi 125, Apto 152, BR-04018050 Sao Paulo, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: OBESITY SURGERY; v. 28, n. 4, p. 1047-1054, APR 2018.
Web of Science Citations: 2
Abstract

The purpose of this study is to correlate the left ventricular hypertrophy (LVH) patterns according to severe obesity and arterial hypertension (AHT) grades. A cross-sectional prospective study was conducted in 379 patients with severe obesity. Obesity was classified according to the BMI in the following: morbidly obese (MO; 40 < BMI < 50 kg/m(2)) and super obese (SO; BMI > 50 kg/m(2)). The AHT was classified into classes 1 and 2 according to American Heart Association. The presence of LVH and the pattern of cardiac remodeling were determined by transthoracic echocardiography. LVH was present in 58.6% of patients. Obesity and AHT had additive effects in LVH prevalence. LVH was found in 32.9 and 46.7% of MO with AHT grades 1 and 2, respectively. LVH was diagnosed in 39.1% in SO with AHT grade 1 and in 50% of AHT grade 2. Patients with AHT presented a significantly higher risk of developing LVH (OR 1.97; p = 0.003). Hypertension grade was also a determinant variable in the development of LVH. Patients with AHT 2 had 4.31-fold greater risk (p < 0.001) when compared to normotensive patients. BMI was only considered an independent risk factor for LVH in patients with BMI greater than 47.17 kg/m(2) (OR 1.62; p = 0.023). AHT is a stronger predictive factor of LVH than obesity grade. (AU)

FAPESP's process: 15/12265-4 - Patterns of cardiac hypertrophy in sever obesity according to the classification of obesity and the severity of sistemic arterial hypertension
Grantee:Victor Arrais Araujo
Support Opportunities: Scholarships in Brazil - Scientific Initiation