Association between obesity and sleep disorders in postmenopausal women

Autor(es)

Naufel, Maria Fernanda ^[1] ; Frange, Cristina ^[2] ; Andersen, Monica Levy ^[2] ; Batista Castello Girao, Manoel Joao ^[3] ; Tufik, Sergio ^[2] ; Ribeiro, Eliane Beraldi ^[1] ; Hachul, Helena ^{[2, 3, 4]}

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo UNIFESP, Dept Physiol, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo UNIFESP, Dept Psychobiol, Sao Paulo - Brazil

^[3] Univ Fed Sao Paulo Unifesp, Dept Gynecol, Sao Paulo - Brazil

^[4] Casa Saude Santa Marcelina, Dept Gynecol, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY; v. 25, n. 2, p. 139-144, FEB 2018.
• Citações Web of Science: 8

Resumo

Objective:To investigate the relationship between obesity and sleep architecture in postmenopausal women.Methods:One hundred seven postmenopausal women from the Ambulatory of Integrative Treatment for Female Sleep Disorders were invited by telephone to participate in this study. Fifty-three completed the study. We included women aged 50 to 70 years, and excluded women on hormone therapy or missing data. The study consisted of two meetings, including a full-night polysomnography. Menopause status was confirmed by amenorrhea for at least 1 year. Anthropometric measurements included: body mass, height, body mass index (BMI), waist circumference, hip circumference, waist-to-hip ratio (WHR), and neck circumference. Participants were allocated into two groups according to BMI: nonobese group (BMI <30kg/m(2)) and obese group (BMI 30kg/m(2)).Results:The obese group had significantly (P<0.01) increased values of BMI, neck circumference, waist circumference, and hip circumference. WHR was similar between the groups (P=0.77). Obese participants had significantly increased values of respiratory disturbance index (16.4 vs 9.3n degrees/h) and apnea-hypopnea index (14.2 vs 5.6n degrees/h). Rapid eye movement sleep latency was positively correlated to body mass (r=P<0.01), BMI (P<0.01), and hip circumference (P=0.01). WHR was negatively correlated to sleep efficiency (P=0.03). The linear regression model showed that BMI (P<0.01) and WHR (P<0.01) were positive predictors of rapid eye movement sleep latency.Conclusion:In postmenopausal women, high BMI and abdominal obesity are sources of sleep disturbances, decreasing deep sleep, and sleep efficiency, while increasing the risk of obstructive sleep apnea. (AU)

• Processo FAPESP: 14/18722-5 - Estudo da insônia associada à dor musculoesquelética em mulheres na pós-menopausa
• Beneficiário: Cristina Mattos Pereira Frange
• Modalidade de apoio: Bolsas no Brasil - Doutorado