Evaluating the impact of measurement uncertainty in blood pressure measurement on hypertension diagnosis

Autor(es)

Rodrigues Filho, Bruno A. ^[1] ; Farias, Rafael F. ^[1] ; dos Anjos, Wilian ^[2]

Afiliação do(s) autor(es)

^[1] Natl Inst Metrol Qual & Technol Inmetro, Dept Legal Metrol, Sao Paulo - Brazil

^[2] Weights & Measures Inst Sao Paulo IPEM SP, Dept Sci & Ind Metrol, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: BLOOD PRESSURE MONITORING; v. 23, n. 3, p. 141-147, JUN 2018.
• Citações Web of Science: 2

Resumo

Background and objectiveThe sphygmomanometer is a well-known device used widely for blood pressure (BP)measurement in primary cares to diagnose hypertension. It is also vastly used by patients to monitor BP for medication. Deviations in measurement might affect significantly the diagnosis. For example, a hypertensive patient might be diagnosed as normal and consequently not receive proper treatment or a healthy patient might be diagnosed as hypertensive and may receive treatment for a nonexistent disease. A measurement has two components, the error and the measurement uncertainty, both affecting the interpretation of the results yielded by the sphygmomanometer. As the impact of measurement uncertainty has not been considered properly, the present study aims to evaluate how it influences the misdiagnosis of hypertension.Materials and methodsA theoretical approach is applied, using two samples from the literature, simulating how the measurement uncertainty affects the diagnosis of a sample with known BP for a sphygmomanometer indicating the threshold pressures of diagnosis. We also carried out a study evaluating how the number of measurements taken affects the probability of misdiagnosis.ResultsFor one of the samples, the results show an increase in misdiagnosis of 227% for diastolic pressure and 225% for systolic pressure, considering the threshold of 90 and 140mmHg, for a measurement error of -5mmHg when considering a 5mmHg uncertainty in comparison with when it is disregarded. The probability of a correct diagnosis also converges to over 98% for four measurements taken.ConclusionThe significant impact of misdiagnosis is an indicator of the importance of considering the uncertainties as a component to medical decision. The number of measurements taken also plays a major role in hypertension diagnosis. Copyright (c) 2018 Wolters Kluwer Health, Inc. All rights reserved. (AU)

• Processo FAPESP: 17/50173-0 - Proposta de ensaio de proficiência aplicado a acreditação no âmbito da metrologia legal na medição de pressão arterial
• Beneficiário: Bruno Amado Rodrigues Filho
• Modalidade de apoio: Auxílio à Pesquisa - Pesquisa em Políticas Públicas