Busca avançada
Ano de início
Entree
(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Low back pain, obesity, and inflammatory markers: exercise as potential treatment

Texto completo
Autor(es):
da Cruz Fernandes, Isabela Maia [1] ; Pinto, Rafael Zambelli [2] ; Ferreira, Paulo [3] ; Lira, Fabio Santos [1]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Sao Paulo State Univ, Fac Sci & Technol, Dept Phys Educ, Exercise & Immunometab Res Grp, Presidente Prudente, SP - Brazil
[2] Univ Fed Minas Gerais, Dept Phys Therapy, Belo Horizonte, MG - Brazil
[3] Univ Sydney, Fac Hlth Sci, Discipline Physiotherapy, Sydney, NSW - Australia
Número total de Afiliações: 3
Tipo de documento: Artigo de Revisão
Fonte: JOURNAL OF EXERCISE REHABILITATION; v. 14, n. 2, p. 168-174, APR 2018.
Citações Web of Science: 3
Resumo

Low back pain is a health issue with significant impact to patients and society. This narrative review aims to synthesize the relationship between obesity, low-grade inflammation and low back pain. It is known that a sedentary lifestyle is a risk factor for obesity and related disorders. The adipose tissue of obese people secretes a range of cytokines of character pro-and anti-inflammatory, with many molecular effects. In addition, pro-inflammatory cytokines are sensitizers of C-reactive protein (CRP), a marker of acute inflammation that can be linked to the musculoskeletal pain sensation individuals with back pain. Another inflammatory marker deserves mention, prostaglandin E-2. Prostaglandin E-2 is important in the process of triggering actions such as pyrexia, sen-sation of pain and inflammation, which are exhibited in low back pain condition. The potential for exercises and physical activity to control these mediators and act as a preventative measure for back pain are important because they work as a nonpharmacological strategy to this target audience. There are two types of exercise discussed in this review, the moderate-intensity continuous training and high-intensity interval training. (AU)

Processo FAPESP: 14/50672-8 - A multicultural project to investigate the relationship between obesity, physical activity, and low back pain
Beneficiário:Fábio Santos de Lira
Modalidade de apoio: Auxílio à Pesquisa - Regular