| Full text | |
| Author(s): |
da Cruz Fernandes, Isabela Maia
[1]
;
Pinto, Rafael Zambelli
[2]
;
Ferreira, Paulo
[3]
;
Lira, Fabio Santos
[1]
Total Authors: 4
|
| Affiliation: | [1] Sao Paulo State Univ, Fac Sci & Technol, Dept Phys Educ, Exercise & Immunometab Res Grp, Presidente Prudente, SP - Brazil
[2] Univ Fed Minas Gerais, Dept Phys Therapy, Belo Horizonte, MG - Brazil
[3] Univ Sydney, Fac Hlth Sci, Discipline Physiotherapy, Sydney, NSW - Australia
Total Affiliations: 3
|
| Document type: | Review article |
| Source: | JOURNAL OF EXERCISE REHABILITATION; v. 14, n. 2, p. 168-174, APR 2018. |
| Web of Science Citations: | 3 |
| Abstract | |
Low back pain is a health issue with significant impact to patients and society. This narrative review aims to synthesize the relationship between obesity, low-grade inflammation and low back pain. It is known that a sedentary lifestyle is a risk factor for obesity and related disorders. The adipose tissue of obese people secretes a range of cytokines of character pro-and anti-inflammatory, with many molecular effects. In addition, pro-inflammatory cytokines are sensitizers of C-reactive protein (CRP), a marker of acute inflammation that can be linked to the musculoskeletal pain sensation individuals with back pain. Another inflammatory marker deserves mention, prostaglandin E-2. Prostaglandin E-2 is important in the process of triggering actions such as pyrexia, sen-sation of pain and inflammation, which are exhibited in low back pain condition. The potential for exercises and physical activity to control these mediators and act as a preventative measure for back pain are important because they work as a nonpharmacological strategy to this target audience. There are two types of exercise discussed in this review, the moderate-intensity continuous training and high-intensity interval training. (AU) | |
| FAPESP's process: | 14/50672-8 - A multicultural project to investigate the relationship between obesity, physical activity, and low back pain |
| Grantee: | Fábio Santos de Lira |
| Support Opportunities: | Regular Research Grants |